CAJ | 학술논문

哺乳动物下丘脑视交叉上核(SCN)是昼夜节律最主要的起搏器，控制着机体的生理和行为的节律。它具有自身内在的节律性，同时也受光照周期信号和一些内源性化学物质的调节。松果腺分泌褪黑素(MEL)受SCN的调控，MEL通过作用于SCN上高亲和性MEL受体，启动第二、第三信使系统，调整SCN的昼夜节律活动。这种调整具有时间敏感性。
포유동물하구뇌시교차상핵(SCN)시주야절률최주요적기박기，공제착궤체적생리화행위적절률。타구유자신내재적절률성，동시야수광조주기신호화일사내원성화학물질적조절。송과선분비퇴흑소(MEL)수SCN적조공，MEL통과작용우SCN상고친화성MEL수체，계동제이、제삼신사계통，조정SCN적주야절률활동。저충조정구유시간민감성。
The hypothalamic suprachiasmatic nucleus (SCN) is a most important circadian pacemaker, which controls physiological and behaviour rhythm in mammals. SCN owns a intrinsic rhythm itself, and is entrained by photoperiodic signal and some endogenous chemicalsubstances. Melatonin (MEL) is secreted by pineal gland, which is regulated by SCN. MEL triggers the second and third message systems, and regulates SCN circadian activity through high affinity MEL receptor within SCN. This regulation is time-sensitive.