CAJ | 학술논문

[目的］分析伽玛刀(γ刀)治疗听神经瘤的疗效及适应证，并发症发生的原因及预防。[方法]采用0UR-XGD旋转式伽玛刀治疗听神经瘤55例，肿瘤平均直径2.9cm，平均肿瘤边缘剂量l4Gy，中心剂量33.6Gy，平均采用的等剂量曲线为48.7％，平均等中心点为4.7个，随访12～35个月。[结果]肿瘤缩小41.8％，肿瘤稳定无增大50.9％，合计肿瘤生长控制率92.7％，肿瘤增大7.3％。听神经保护率40％，面神经保护率89.8％，无死亡病例。[结论]γ刀治疗听神经瘤具有较高的肿瘤生长控制率，死亡率极小，且可保护颅神经功能，是一种有效的治疗方法。
[목적］분석가마도(γ도)치료은신경류적료효급괄응증，병발증발생적원인급예방。[방법]채용0UR-XGD선전식가마도치료은신경류55례，종류평균직경2.9cm，평균종류변연제량l4Gy，중심제량33.6Gy，평균채용적등제량곡선위48.7％，평균등중심점위4.7개，수방12～35개월。[결과]종류축소41.8％，종류은정무증대50.9％，합계종류생장공제솔92.7％，종류증대7.3％。은신경보호솔40％，면신경보호솔89.8％，무사망병례。[결론]γ도치료은신경류구유교고적종류생장공제솔，사망솔겁소，차가보호로신경공능，시일충유효적치료방법。
[Purpose] To study the effect of gamma knife for acoustic neurianomas. [Methods]Fifty4ive patients with acoustic neurianomas treated with OUR - XGD rotating gamma knife. The average of tumor's diameter was 2.9cm. The average tumor peripheral dose was 14 Gy ( 11Gy ～ 20Gy),the center dose was 35.6Gy (21Gy ～ 40Gy) .The mean isodose curve was 48.7% ,the average of shots was 4.7 points. Follow-up ranged from 12 to 35 months. [Result] Tumors reduced in 23 of 55 patients (41.8%) and stable in 28 of 55 patients (50.9%) .The response rate was 92.7% .The tumor progressed in 4 cases of this group. The audition preservation rate was 40%. The facial neuropathic protection rate was 89.8%. No one died.[ Conclusion ] Gamma knife is an effective treatment for acoustic neurianomas with higher response rate, lower mortality, and less side effect for cranial nerve.