压力负荷型心肌肥厚大鼠心肌组织相关基因的分离
압력부하형심기비후대서심기조직상관기인적분리
Isolation of Related Genes of Cardiac Hypertrophy in Pressure overloaded Rat Models with Subtractive Hybridization
  • 万方数据
    中国生物化学与分子生物学报 중국생물화학여분자생물학보
    CHINESE JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
    2000年 2期 285-287 ,共3页

    田靫%潘德思%陈兰英

    전채%반덕사%진란영



    ardiac hypertrophy%Subtractive hybridization


    Cardiac hypertrophy is intensively related with the morbidity of heart failure,atherosclerosis and stroke. The rat models of left ventricular hypertrophy caused by abdominal aorta constriction and the method of subtractive hybridization to isolate genes expressing differently were used during cardiac hypertrophy. 24 cDNA segments were isolated and identified by colony and dot hybridization. Sequence homogenous comparison showed that some of them were very similar to known genes or segments, others were limitedly homogenous and the rest were not found to be significantly homogenous.
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