CAJ | 학술논문

对云南大理产腺花香茶菜(Isodon adenanthus)进行了系统的研究.从中分离得到了包括1个新三萜(1)在内的一系列乌索烷型三萜类化合物,其结构通过现代波谱分析方法确定.活性筛选结果表明,化合物1对肿瘤细胞株K562,A549以及T24具有一定的细胞毒活性.
대운남대리산선화향다채(Isodon adenanthus)진행료계통적연구.종중분리득도료포괄1개신삼첩(1)재내적일계렬오색완형삼첩류화합물,기결구통과현대파보분석방법학정.활성사선결과표명,화합물1대종류세포주K562,A549이급T24구유일정적세포독활성.
Further investigation on the leaves of Isodon adenanthus afforded a new triterpenoid, isodonadenanthin (1), together with three known ones, ursolic acid, 2αhydroxylursolic acid and 2α, 24dihydroxylursolic acid. Structures of 14 were elucidated on the basis of their spectral properties. The cytotoxicities of the new compound against three kinds of human tumor cells K562, A549, and T24 were also tested. And1showed a certain antitumor activities toward all three kinds of cells.