CAJ | 학술논문

研究锰对大鼠子代不同时期血液中必需微量元素的影响。将妊娠大鼠随机分为4组，腹腔内注射氯化锰，剂量分别为0，7.5，15，30mg/kg，待其自然分娩后采用原子吸收光谱法测定其子代新生鼠及20日龄鼠血液中微量元素锰、铜和锌含量。实验各组新生鼠血液中锰含量高于对照组(P＜0.01)，而各组20日龄仔鼠血液中锰含量盖异无量著性(P＞0.05)；各实验组新生鼠和20日龄鼠血液中锌含量均明显降低(P＜0.05，P＜0.01);实验各组新生鼠及20日龄鼠血液中铜含量与对照组差异均无显著性(P＞0.05)。研究表明，大鼠孕期染锰使其新生鼠及20日龄仔鼠血液中锰、锌等的含量发生变化，影响了锰、锌在体内的代谢，对其生长发育产生不利影响。
연구맹대대서자대불동시기혈액중필수미량원소적영향。장임신대서수궤분위4조，복강내주사록화맹，제량분별위0，7.5，15，30mg/kg，대기자연분면후채용원자흡수광보법측정기자대신생서급20일령서혈액중미량원소맹、동화자함량。실험각조신생서혈액중맹함량고우대조조(P＜0.01)，이각조20일령자서혈액중맹함량개이무량저성(P＞0.05)；각실험조신생서화20일령서혈액중자함량균명현강저(P＜0.05，P＜0.01);실험각조신생서급20일령서혈액중동함량여대조조차이균무현저성(P＞0.05)。연구표명，대서잉기염맹사기신생서급20일령자서혈액중맹、자등적함량발생변화，영향료맹、자재체내적대사，대기생장발육산생불리영향。
To study the effects of manganese on the essential microelements in the blood of filial rats in different periods after mother-rats were exposed by manganese ,impregnated female rats were injected intraabdominally with 0,7. 5,15,30mg/kg MnCl2 for 8 times every other day,and the contents of Mn, Cu and Zn in the blood of newborn rats and 20-day-old rats were determined with atomic absorption spectroscopy. The contents of Mn in the blood of new-born rats of three experimental groups have significantly increased compared with the control group (P＜0. 01)while the contents of Mn were not significantly different in the blood of 20-day-old rats among four groups (P＞0. 05). The levels of Zn in the blood of new-born rats and 20-day-old rats of three experimental groups were lower than those of the control groups(P＜0. 05,P＜0. 01). The levels of Cu demonstrated no significant difference among four groups (P＞0. 05). After impregnated female rats were exposed to manganese, their filial rats' metabolism of Mn and Zn in the blood were influenced. Their filial rats' growth and development could be harmed.