中国男科学杂志
中國男科學雜誌
중국남과학잡지
CHINESE JOURNAL OF ANDROLOGY
2009年
12期
32-35,41
,共5页
王翔%黄炯伟%付伟金%瞿连喜
王翔%黃炯偉%付偉金%瞿連喜
왕상%황형위%부위금%구련희
勃起功能障碍%肾移植
勃起功能障礙%腎移植
발기공능장애%신이식
erectile dysfunction%kidney transplantation
目的 研究男性肾移植患者术后勃起功能障碍 (ED)的相关影响因素.方法 随机选择25～57岁、术后半年以上、血肌酐133μmol/L以下的已婚男性肾移植受者50例,采用勃起功能国际问卷(IIEF-5)对其肾移植前后勃起功能进行评估,并应用多因素Logistic回归分析,确定对勃起功能有影响的相关因素.结果 肾移植术前有41例(82%)被诊断为不同程度的ED,移植术后26例被确定为ED(52%),术前与术后比较差异有统计学意义(P<0.05).Logistic回归分析表明,年龄、血液透析时间、移植肾动脉吻合方式和以环孢素(CsA)为基础的免疫抑制剂治疗是影响勃起功能的独立和显著因素(P<0.05),相对危险度分别为3.06、2.03、3.93、2.74.结论 成功的肾移植术可改善患者的勃起功能,但仍有着较高的ED发生率,年龄、血液透析时间、术中移植肾动脉吻合方式、以CsA为基础的免疫抑制剂治疗是影响勃起功能的主要因素.
目的 研究男性腎移植患者術後勃起功能障礙 (ED)的相關影響因素.方法 隨機選擇25～57歲、術後半年以上、血肌酐133μmol/L以下的已婚男性腎移植受者50例,採用勃起功能國際問捲(IIEF-5)對其腎移植前後勃起功能進行評估,併應用多因素Logistic迴歸分析,確定對勃起功能有影響的相關因素.結果 腎移植術前有41例(82%)被診斷為不同程度的ED,移植術後26例被確定為ED(52%),術前與術後比較差異有統計學意義(P<0.05).Logistic迴歸分析錶明,年齡、血液透析時間、移植腎動脈吻閤方式和以環孢素(CsA)為基礎的免疫抑製劑治療是影響勃起功能的獨立和顯著因素(P<0.05),相對危險度分彆為3.06、2.03、3.93、2.74.結論 成功的腎移植術可改善患者的勃起功能,但仍有著較高的ED髮生率,年齡、血液透析時間、術中移植腎動脈吻閤方式、以CsA為基礎的免疫抑製劑治療是影響勃起功能的主要因素.
목적 연구남성신이식환자술후발기공능장애 (ED)적상관영향인소.방법 수궤선택25～57세、술후반년이상、혈기항133μmol/L이하적이혼남성신이식수자50례,채용발기공능국제문권(IIEF-5)대기신이식전후발기공능진행평고,병응용다인소Logistic회귀분석,학정대발기공능유영향적상관인소.결과 신이식술전유41례(82%)피진단위불동정도적ED,이식술후26례피학정위ED(52%),술전여술후비교차이유통계학의의(P<0.05).Logistic회귀분석표명,년령、혈액투석시간、이식신동맥문합방식화이배포소(CsA)위기출적면역억제제치료시영향발기공능적독립화현저인소(P<0.05),상대위험도분별위3.06、2.03、3.93、2.74.결론 성공적신이식술가개선환자적발기공능,단잉유착교고적ED발생솔,년령、혈액투석시간、술중이식신동맥문합방식、이CsA위기출적면역억제제치료시영향발기공능적주요인소.
Objective To investigate the related factors with erectile dysfunction (ED) of male patients after kidney transplantation.Methods Fifty treated male patients by kidney transplantation at least half a year,with serum creatinine level under 133umol/l,were enrolled in the study.Structured questionnaires were administrated by trained interviewers.International index of erectile function-5 (IIEF-5) was employed to evaluate ED before and after kidney transplantation,and levels of sex hormones were measured.Multivariate logistic regression was used to analyze the relationship of sexual dysfunction and other medical indexes.Results The prevalence of ED in patients was 82%(41/50) before kidney transplantation and it decreased to 52%(26/50) after transplantation (P＜0.05).Logistic regression analysis showed age,duration of haemodialysis,style of anastomosis,CsA treatment were independent risk factors for ED in the treated patients with kidney transplantation (P＜0.05).Their relative risks were 3.06,2.03,3.93 and 2.74 respectively.Conclusion Occurrence of ED was highly prevalent among kidney transplantation patients and its pathogenesis was complex and multifactors-involving.Age,duration of haemodialysis,style of anastomosis and CsA treatment were chief risk factors of erectile function.
