CAJ | 학술논문

目的研究上海地区成年人全血微量元素与血脂和血糖的关系.方法选择上海地区2个社区18岁以上成年调查对象245名,测定其体内铁(Fe)、锌(Zn)、铜(Cu)、镁(Mg)、铅(Pb)、锰(Mn)、镉(Cd)等各种元素含量及体重指数(BMI)、腰臀比(WHR)和血压水平,分析上述指标与血脂和血糖之间的关系.结果与正常对照组相比,高脂血症组全血Fe、Mn水平显著降低,Zn、Zn/Cu水平显著升高(P＜0.05或P＜0.01);高血糖组全血Zn、Zn/Cu和Mn水平显著降低,Cu和Pb水平显著升高(P＜0.05或P＜0.01);在高脂血症和高血糖组均存在低Mg高cd趋势,但差异无统计学意义(P＞0.05).结论高脂血症和高血糖患者体内大多数微量元素都存在代谢异常,及时纠正微量元素代谢紊乱对高脂血症和高血糖的防治和转归可能具有一定价值.
목적 연구상해지구성년인전혈미량원소여혈지화혈당적관계.방법 선택상해지구2개사구18세이상성년조사대상245명,측정기체내철(Fe)、자(Zn)、동(Cu)、미(Mg)、연(Pb)、맹(Mn)、력(Cd)등각충원소함량급체중지수(BMI)、요둔비(WHR)화혈압수평,분석상술지표여혈지화혈당지간적관계.결과 여정상대조조상비,고지혈증조전혈Fe、Mn수평현저강저,Zn、Zn/Cu수평현저승고(P＜0.05혹P＜0.01);고혈당조전혈Zn、Zn/Cu화Mn수평현저강저,Cu화Pb수평현저승고(P＜0.05혹P＜0.01);재고지혈증화고혈당조균존재저Mg고cd추세,단차이무통계학의의(P＞0.05).결론 고지혈증화고혈당환자체내대다수미량원소도존재대사이상,급시규정미량원소대사문란대고지혈증화고혈당적방치화전귀가능구유일정개치.
Objective To study the relationship between trace elements and blood lipids and glucose in Shanghai adults. Methods Totally 245 subjects aged above 18 years from two communities in Shanghai were en-rolled into this study. Blood trace elements (Fe, Zn, Cu, Mg, Pb, Mn, and Cd) were examined with atom ab-serption spectrophotometry. Body mass index (BMI), waist hip rate (WHR), and blood pressure (SBP, DBP)were also determined. Results Compared with the normal control group, plasma Fe and Mn levels were signifi-cantly lower while Zn and Zn/Cu levels were significantly higher in hyperlipemia group (P <0.05 or P <0. 01 ) ;plasma Zn, Zn/Cu, and Mn levels were significantly lower while Cu and Pb levels were significantly higher in dia- betes mellitus group (P <0. 05 or P <0. 01 ) . A tendency of lower Mg and higher Cd levels were also found in both disease groups, but there were no statistical significance ( P >0. 05 ). Conclusions The metabolism of trace elements is abnormal in patients with hyperlipemia and diabetes mellitus. Intervention of these trace elements disor-der may be valuable in the prevention and treatment of these diseases.