中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2010年
7期
551-554
,共4页
吴静%方祖伦%朱昱思%张巳声%龚念梅
吳靜%方祖倫%硃昱思%張巳聲%龔唸梅
오정%방조륜%주욱사%장사성%공념매
多普勒组织成像%心肌病,扩张型%心室功能,左
多普勒組織成像%心肌病,擴張型%心室功能,左
다보륵조직성상%심기병,확장형%심실공능,좌
Doppler tissue imaging%Cardiomyopathy,dilated%Ventricular function,left
目的 应用多普勒组织成像(doppler tissue imaging,DTI)技术评价老年扩张型心肌病(dilated cardiomyopathy,DCM)患者左室舒缩功能,并探讨其临床应用价值.方法 采集健康老年人20例(对照组)和老年DCM患者22例(DCM组).用常规超声心动图分别测量左审舒张末期内径(LVEDd)、左房内径(LAD)和左室射血分数(LVEF);在DTI模式下,用定量组织速度图(QTVI)分别测量二尖瓣环水平6个位点的收缩期峰值速度(Vs)和舒张早期峰值速度(Ve),并计算其平均值;用组织追踪图(TTI)显示二尖瓣环水平6个位点收缩期位移(mvd),并计算其平均值.结果 DCM患者LVEDd(67.56±10.27)mm、LAD(49.91±6.27)mm,较对照组[43.36±4.20)mm、(32.00±4.53)mm]明显增大(t值分别为10.229、10.359,均P<0.01);LVEF(26.50±8.25)%、Vs(5.14±1.30)cm/s、mvd(4.82 4±1.85)mm.均较对照组[64.00±4.72)%、(8.89±1.87)cm/s、(10.23±1.95)mm]减低(t值分别为18.502、7.716,8.143.均P<0.01);Vs、mvd与LVEF呈显著正相关(r值分别为0.78、0.89.均P<0.01).结论 DTI可以直观、准确评价老年DCM患者左室整体和局祁的舒缩功能,为判断病情提供可靠的信息依据.
目的 應用多普勒組織成像(doppler tissue imaging,DTI)技術評價老年擴張型心肌病(dilated cardiomyopathy,DCM)患者左室舒縮功能,併探討其臨床應用價值.方法 採集健康老年人20例(對照組)和老年DCM患者22例(DCM組).用常規超聲心動圖分彆測量左審舒張末期內徑(LVEDd)、左房內徑(LAD)和左室射血分數(LVEF);在DTI模式下,用定量組織速度圖(QTVI)分彆測量二尖瓣環水平6箇位點的收縮期峰值速度(Vs)和舒張早期峰值速度(Ve),併計算其平均值;用組織追蹤圖(TTI)顯示二尖瓣環水平6箇位點收縮期位移(mvd),併計算其平均值.結果 DCM患者LVEDd(67.56±10.27)mm、LAD(49.91±6.27)mm,較對照組[43.36±4.20)mm、(32.00±4.53)mm]明顯增大(t值分彆為10.229、10.359,均P<0.01);LVEF(26.50±8.25)%、Vs(5.14±1.30)cm/s、mvd(4.82 4±1.85)mm.均較對照組[64.00±4.72)%、(8.89±1.87)cm/s、(10.23±1.95)mm]減低(t值分彆為18.502、7.716,8.143.均P<0.01);Vs、mvd與LVEF呈顯著正相關(r值分彆為0.78、0.89.均P<0.01).結論 DTI可以直觀、準確評價老年DCM患者左室整體和跼祁的舒縮功能,為判斷病情提供可靠的信息依據.
목적 응용다보륵조직성상(doppler tissue imaging,DTI)기술평개노년확장형심기병(dilated cardiomyopathy,DCM)환자좌실서축공능,병탐토기림상응용개치.방법 채집건강노년인20례(대조조)화노년DCM환자22례(DCM조).용상규초성심동도분별측량좌심서장말기내경(LVEDd)、좌방내경(LAD)화좌실사혈분수(LVEF);재DTI모식하,용정량조직속도도(QTVI)분별측량이첨판배수평6개위점적수축기봉치속도(Vs)화서장조기봉치속도(Ve),병계산기평균치;용조직추종도(TTI)현시이첨판배수평6개위점수축기위이(mvd),병계산기평균치.결과 DCM환자LVEDd(67.56±10.27)mm、LAD(49.91±6.27)mm,교대조조[43.36±4.20)mm、(32.00±4.53)mm]명현증대(t치분별위10.229、10.359,균P<0.01);LVEF(26.50±8.25)%、Vs(5.14±1.30)cm/s、mvd(4.82 4±1.85)mm.균교대조조[64.00±4.72)%、(8.89±1.87)cm/s、(10.23±1.95)mm]감저(t치분별위18.502、7.716,8.143.균P<0.01);Vs、mvd여LVEF정현저정상관(r치분별위0.78、0.89.균P<0.01).결론 DTI가이직관、준학평개노년DCM환자좌실정체화국기적서축공능,위판단병정제공가고적신식의거.
Objective To quantitatively assess the left ventricular systolic and diastolic function in the elderly patients with dilated cardiomyopathy (DCM) by using Doppler tissue imaging (DTI) and to explore its clinical value. Methods A total of 20 normal controls and 22 old patients with DCM were enrolled in the study. The left ventricular end-diastolic diameter (LVEDd), left atrial diameter (LAD) and left ventricle ejection fraction(LVEF) were obtained by routine echocardiogram. And the systolic and early diastolic peak velocity (Vs and Ve) were detected by quantitative tissue velocity imaging (QTVI) and the mean value was accounted. The systolic mitral valve displacements (MVD) in 6 sites were determined by tissue tracking technique and the mean value was calculated. Results The LVEDd and LAD were significantly higher in DCM group than in normal group [LVEDd: (67.56±10.27) mm vs. (43.36±4.20) mm; LAD: (49.91± 6.27) mm vs. (32.00+4.53) mm, t=10.229 and 10.359, both P<0.01]. And the LVEF, Vs and MVD were lower in DCM group than in normal group [LVEF: (26.50 ± 8.25)% vs. (64.00 + 4.72)%; Vs:(5.14+1.30) cm/s vs. (8.89+1.87) cm/s; MVD:4.82+1.85 vs. 10.23± 1.95, t=18.502, 7.716 and 8.143, all P< 0.01].The Vs and MVD were significantly positively correlated with LVEF (r=0.78 and 0.89, both P<0.01). Conclusions DTI can quantitatively assess global and regional left ventricular systolic and diastolic function of elderly patients with DCM, and provide the reliable information for the judgment of pathogenetic condition.