中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2010年
9期
927-930
,共4页
张旭%孙振学%吕豪%邸茹杰
張旭%孫振學%呂豪%邸茹傑
장욱%손진학%려호%저여걸
踝臂指数%冠心病%外周动脉疾病%危险因素
踝臂指數%冠心病%外週動脈疾病%危險因素
과비지수%관심병%외주동맥질병%위험인소
Ankle-brachial index%Coronary heart disease%Peripheral arterial disease%Risk factors
目的 观察冠心病及等危症患者合并外周动脉疾病(PAD)的发病情况,探讨踝臂指数(ABI)在临床上的应用价值.方法 选取621例冠心病及等危症患者,收集相关临床资料并检测相关生化指标,采用科林动脉硬化检测仪测量受试者的ABI值,应用SPSS 13.0统计软件进行数据分析和处理.结果 冠心病及等危症患者中合并PAD者为169例,总的患病率为27.2%,女性PAD的患病率[34.6%(129/373)]明显高于男性[16.1%(40/248),P＜0.01].PAD组年龄、总胆固醇显著高于非PAD组[年龄分别为(65±10)、(60±10)岁,t值为5.847;总胆固醇分别为(5.4±1.1)、(5.1±1.1)mmol/L,t值为2.626;P均＜0.01],多因素Logistic回归分析显示,性别(OR 0.35,95% CI 0.214～0.572)、年龄(OR 1.05,95% CI 1.024～1.072)、总胆固醇(OR 1.52,95% CI 1.089～2.129)是高危患者伴PAD的危险因素(P均＜0.05);同时患有冠心病、糖尿病和缺血性脑卒中三种疾病的患者PAD患病率达50.0%.结论 ABI是筛查冠心病及等危症患者伴PAD的简单易行又可靠的指标,性别、年龄、总胆固醇是冠心病及等危症患者ABI降低的危险因素.
目的 觀察冠心病及等危癥患者閤併外週動脈疾病(PAD)的髮病情況,探討踝臂指數(ABI)在臨床上的應用價值.方法 選取621例冠心病及等危癥患者,收集相關臨床資料併檢測相關生化指標,採用科林動脈硬化檢測儀測量受試者的ABI值,應用SPSS 13.0統計軟件進行數據分析和處理.結果 冠心病及等危癥患者中閤併PAD者為169例,總的患病率為27.2%,女性PAD的患病率[34.6%(129/373)]明顯高于男性[16.1%(40/248),P＜0.01].PAD組年齡、總膽固醇顯著高于非PAD組[年齡分彆為(65±10)、(60±10)歲,t值為5.847;總膽固醇分彆為(5.4±1.1)、(5.1±1.1)mmol/L,t值為2.626;P均＜0.01],多因素Logistic迴歸分析顯示,性彆(OR 0.35,95% CI 0.214～0.572)、年齡(OR 1.05,95% CI 1.024～1.072)、總膽固醇(OR 1.52,95% CI 1.089～2.129)是高危患者伴PAD的危險因素(P均＜0.05);同時患有冠心病、糖尿病和缺血性腦卒中三種疾病的患者PAD患病率達50.0%.結論 ABI是篩查冠心病及等危癥患者伴PAD的簡單易行又可靠的指標,性彆、年齡、總膽固醇是冠心病及等危癥患者ABI降低的危險因素.
목적 관찰관심병급등위증환자합병외주동맥질병(PAD)적발병정황,탐토과비지수(ABI)재림상상적응용개치.방법 선취621례관심병급등위증환자,수집상관림상자료병검측상관생화지표,채용과림동맥경화검측의측량수시자적ABI치,응용SPSS 13.0통계연건진행수거분석화처리.결과 관심병급등위증환자중합병PAD자위169례,총적환병솔위27.2%,녀성PAD적환병솔[34.6%(129/373)]명현고우남성[16.1%(40/248),P＜0.01].PAD조년령、총담고순현저고우비PAD조[년령분별위(65±10)、(60±10)세,t치위5.847;총담고순분별위(5.4±1.1)、(5.1±1.1)mmol/L,t치위2.626;P균＜0.01],다인소Logistic회귀분석현시,성별(OR 0.35,95% CI 0.214～0.572)、년령(OR 1.05,95% CI 1.024～1.072)、총담고순(OR 1.52,95% CI 1.089～2.129)시고위환자반PAD적위험인소(P균＜0.05);동시환유관심병、당뇨병화결혈성뇌졸중삼충질병적환자PAD환병솔체50.0%.결론 ABI시사사관심병급등위증환자반PAD적간단역행우가고적지표,성별、년령、총담고순시관심병급등위증환자ABI강저적위험인소.
Objective To observe the proportion of the peripheral artery disease (PAD) in patients with equal-risk to coronary heart disease and to explore the clinical value of ankle brachial index(ABI). Methods Six hundred and twenty-one cases with equal-risk to coronary heart disease were recruited to the study. Their clinical data and biochemical indicators were collected for further analysis. The value of ABI, which was popularly used in screening PAD, was measured by Oscillometric measurement. All data were statistically analyzed by SPSS 13.0 software. Results There were 169 cases had PAD,the proportion of it was 27.2%. The proportion of PAD in male and female were 34.6% and 16.1% respectively,which had significant difference(P ＜0.01). Compared with NonPAD group,the average age (65 ± 10 years vs. 60 ± 10 years,P ＜0.01) and total cholesterol level (5.4 ± 1.1 mmol/L vs. (5.1 ± 1.1) mtool/L, P ＜ 0.01) were significantly higher in PAD group. Logistic regression analysis showed that gender,age and total cholesterol were major risk factors of PAD in patients with equal-risk to coronary heart disease. Proportion of PAD was up to 50.0% in patients with combined coronary heart disease,ischemic stroke and diabetes. Conclusions ABI is a feasible and reliable index for screening PAD in patients with equal-risk to coronary heart disease. Gender,age and total cholesterol are major risk factors of low ABI in patients with equal-risk to coronary heart disease.
