CAJ | 학술논문

目的观察心肌梗死恢复期患者在症状限制性运动试验和运动训练期后心肌钙蛋白Ⅰ的变化.方法 20例心肌梗死恢复期中度心力衰竭患者与15例轻度心力衰竭患者及10例无心力衰竭受试者进行对比观察,他们均进行了症状限制性运动试验和单期运动训练(达最大心率的80%以上,持续时间30 min),分别测定其基础肌钙蛋白(CTNI)值、症状限制性试验后和运动训练后1～5 h时的CTNI值.结果症状限制性运动试验后,中度心力衰竭患者CNTI值由(38±19)pg/ml增加到(75±29)pg/ml,其中5例中度心力衰竭患者和4例轻度心力衰竭患者的CNTI值升高到100 pg/ml以上.无心力衰竭的受试者无论是静息时或是运动后其CNTI值均较低(P<0.05).结论心肌梗死恢复期中度心力衰竭患者在症状限制性运动试验后其CNTI值增加,其水平达到轻微的心肌损伤水平,这一现象对患者预后的影响值得进一步研究.
목적 관찰심기경사회복기환자재증상한제성운동시험화운동훈련기후심기개단백Ⅰ적변화.방법 20례심기경사회복기중도심력쇠갈환자여15례경도심력쇠갈환자급10례무심력쇠갈수시자진행대비관찰,타문균진행료증상한제성운동시험화단기운동훈련(체최대심솔적80%이상,지속시간30 min),분별측정기기출기개단백(CTNI)치、증상한제성시험후화운동훈련후1～5 h시적CTNI치.결과 증상한제성운동시험후,중도심력쇠갈환자CNTI치유(38±19)pg/ml증가도(75±29)pg/ml,기중5례중도심력쇠갈환자화4례경도심력쇠갈환자적CNTI치승고도100 pg/ml이상.무심력쇠갈적수시자무론시정식시혹시운동후기CNTI치균교저(P<0.05).결론 심기경사회복기중도심력쇠갈환자재증상한제성운동시험후기CNTI치증가,기수평체도경미적심기손상수평,저일현상대환자예후적영향치득진일보연구.
Objective To study whether an increase of cardiac troponin Ⅰ(cTnI) can be observed after symptom - limited exercise and an exercise training session in patients with myocardial infarction(MI). Methods Twenty eases of MI and moderate heart failure were compared with 15 patients with MI and mild heart failure and 10 normal subjects without heart failure. All subjects underwent a symptom - limited test and an exercise training session at > 80% of maximal heart rate over dine 30 minutes. The plasma cTnI level were measured at baseline,after symptom - limited exercise hourly for 5 hours,and 1 to 5 hours after train-ing. Results Patients with MI and moderate heart failure showed an increase of cTnI from(38±19) pg/ml to (75±29) pg/ml(P<0.01) after symptom - limited exercise. Five patients with moderate and two patients with mild heart failure and normal cT-nI values at rest showed the increase of cTnI above 100 pg/ml after acute exercise but not after training. Subjects without heart failure had lower cTnI levels at rest and significantly lower values after symptom - limited exercise and training(P<0.05 for each). Conclusion Patients with MI and symptomatic heart failure show an increase of cTnI after symptom - limited exercise at levels that indicate minor myocardial damage. The prognostic impact of this finding should be further investigated.