CAJ | 학술논문

孕前人体质量指数与妊娠高血压综合征的关系
잉전인체질량지수여임신고혈압종합정적관계
The relationship between prepregnancy body mass index and the occurrence of pregnancy induced hypertension

万方数据

中华预防医学杂志中華預防醫學雜誌 중화예방의학잡지
CHINESE JOURNAL OF
2009年 4期 299-304 ,共6页

刘英惠%刘建蒙%刘兰%马蕊%叶荣伟%李松%陈华%薛明君%成伶春%吴立民%潘玉娟%陈浩%李竹

류영혜%류건몽%류란%마예%협영위%리송%진화%설명군%성령춘%오립민%반옥연%진호%리죽

妊娠%高血压%人体质量指数%身高%体重妊娠%高血壓%人體質量指數%身高%體重
임신%고혈압%인체질량지수%신고%체중
Pregnancy%Hypertension%Body mass index%Body height%Body weight

目的了解孕前人体质量指数(body mass index,BMI)与妊娠高血压综合征(pregnancy-induced hypertension,PIH)发生危险性之间的关系.方法数据来自"中美预防出生缺陷和残疾合作项目"中嘉兴地区的围产保健监测数据库.研究对象为1995-2000年在嘉兴地区参加婚前或孕前体检且分娩了单胎活产儿的孕满20周的83 159名孕产妇.运用X2检验或X<,趋势>2检验比较不同BMI组或其他特征人群PIH发病率的差别,利用多元logistic回归分析孕前BMI与PIH发生危险性之间的关系.结果 PIH发病率为11.01%(9153/83 159;95%CI:10.79%～11.22%).PIH的发病率自BMI<18.5 kg/m2组的9.08%(1405/15 472;95%CI:8.63%～9.54%),18.5～22.9 kg/m2组的10.82%(6389/59 054;95%CI:10.57%～11.07%),23.0～24.9 kg/m2组的14.63%(943/6444;95%CI:13.78%～15.52%)升至BMI≥25/0 kg/m2组的19.00%(416/2189;95%CI:17.38%～20.71%),差异有统计学意义(X<,趋势>2=261.028,P=0.000).以BMI为18.5～22.9 kg/m2者为参照组,BMI<18.5 kg/m2、23.0～24.9 kg/m2和≥25.0 kg/m2组发生PIH的RR值分别为0.82(95%CI:0.77～0.87)、1.41(95%CI:1.31～1.52)和1.93(95%CI:1.73～2.16).调整地区、年龄、文化程度、职业、产次、产前检查次数和既往高血压病史或家族史后,上述RR值分别为0.85(95%CI:0.80～0.90)、1.37(95%CI:1.27～1.47)和1.88(95%CI:1.68～2.10).结论 PIH的发生危险随孕前BMI的升高而升高.
목적 료해잉전인체질량지수(body mass index,BMI)여임신고혈압종합정(pregnancy-induced hypertension,PIH)발생위험성지간적관계.방법 수거래자"중미예방출생결함화잔질합작항목"중가흥지구적위산보건감측수거고.연구대상위1995-2000년재가흥지구삼가혼전혹잉전체검차분면료단태활산인적잉만20주적83 159명잉산부.운용X2검험혹X<,추세>2검험비교불동BMI조혹기타특정인군PIH발병솔적차별,이용다원logistic회귀분석잉전BMI여PIH발생위험성지간적관계.결과 PIH발병솔위11.01%(9153/83 159;95%CI:10.79%～11.22%).PIH적발병솔자BMI<18.5 kg/m2조적9.08%(1405/15 472;95%CI:8.63%～9.54%),18.5～22.9 kg/m2조적10.82%(6389/59 054;95%CI:10.57%～11.07%),23.0～24.9 kg/m2조적14.63%(943/6444;95%CI:13.78%～15.52%)승지BMI≥25/0 kg/m2조적19.00%(416/2189;95%CI:17.38%～20.71%),차이유통계학의의(X<,추세>2=261.028,P=0.000).이BMI위18.5～22.9 kg/m2자위삼조조,BMI<18.5 kg/m2、23.0～24.9 kg/m2화≥25.0 kg/m2조발생PIH적RR치분별위0.82(95%CI:0.77～0.87)、1.41(95%CI:1.31～1.52)화1.93(95%CI:1.73～2.16).조정지구、년령、문화정도、직업、산차、산전검사차수화기왕고혈압병사혹가족사후,상술RR치분별위0.85(95%CI:0.80～0.90)、1.37(95%CI:1.27～1.47)화1.88(95%CI:1.68～2.10).결론 PIH적발생위험수잉전BMI적승고이승고.
Objective To examine the relationship between prepregnancy body mass index (BMI) and the risk of pregnancy-induced hypertension (PIH) in Chinese population. Methods Data were collected in 6 counties/cities covered by Perinatal Health Care Surveillance System which was part of the Sino-American cooperative project on neural tube defects prevention established in 1992. The study population consisted of 83 159 women who attended premarital or preconception medical physical examination and delivered single live births with at least 20 gestational weeks from 1995 to 2000 in Jiaxing area. The Chi-square test was employed to test the difference in the rates of PIH among groups with different BMI. Multivariate logistic regression was conducted to examine the association between prepregnancy BMI and the risk of PIH. Results The rate of PIH was 11.01% (9153/83159;95% CI: 10.79%-11.22%). The rate of PIH among women with BMI <18.5 kg/m2>, 18.5-22.9 kg/m2,23.0-24.9 kg/m2, and ≥25.0 kg/m2(6389/59 054;95% CI: 10. 57%-11.07% ), 14.63% (943/6444; 95% CI: 13.78% - 15.52% ), and 19. 00% (416/2189; 95% CI: 17. 38% - 20. 71% ), respectively, the difference was significant (X<,trend>2 =261.028, P=0.000). Taking those with BMI 18.5-22.9 kg/m2 as reference,the unadjusted RR for PIH was 0. 82 (95% CI: 0.77-0.87) among women with BMI < 18.5 kg/m2, 1.41 (95% CI: 1.31-1.52) among women with BMI 23.0-24.9 kg/m2, and 1.93 (95% CI: 1.73 - 2. 16 ) among women with BMI ≥ 25.0 kg/m2. After controlling for area, maternal age at delivery, educational level, occupation, parity, times of prenatal visit as well as the individual or family history of chronic hypertension, the estimated RR were 0. 85 (95 % CI:0. 80 -0.90),1.37(95% CI:1.27 -1.47) and 1.88(95% CI:1.68-2.10),respectively. Conclusion High prepregnancy BMI could increase the risk of PIH.