CAJ | 학술논문

目的观察乳腺癌术后化疗配合中药天芝草胶囊的减毒增效作用.方法 66例乳腺癌根治术后患者随机分成治疗组31例和对照组35例.对照组采用CAF及TA化疗方案,治疗组化疗同时合用天芝草胶囊口服.观察治疗前后恶心呕吐、骨髓抑制情况,对患者进行生活质量评分.结果治疗组在治疗中骨髓抑制及恶心呕吐发生率明显低于对照组(P<0.05),生存质量改善稳定率明显高于对照组(P<0.05).结论中药天芝草胶囊对乳腺癌术后化疗有减毒增效的作用.
목적 관찰유선암술후화료배합중약천지초효낭적감독증효작용.방법 66례유선암근치술후환자수궤분성치료조31례화대조조35례.대조조채용CAF급TA화료방안,치료조화료동시합용천지초효낭구복.관찰치료전후악심구토、골수억제정황,대환자진행생활질량평분.결과 치료조재치료중골수억제급악심구토발생솔명현저우대조조(P<0.05),생존질량개선은정솔명현고우대조조(P<0.05).결론 중약천지초효낭대유선암술후화료유감독증효적작용.
Objective To observe attenuation and synergy of postoperative chemotherapy combined with Tianzhicao capsule in patients who suffered from breast cancer. Methods 66 cases after radical mastectomy were randomly divided into treatment group 31 cases and 35 cases of control group. The patients of control group were treated with chemotherapies of CAF and TA. Treatment group patients were given Tianzhical capsule orally at the same time. Nausea and vomitting,the arrest of bone marrow before and after treatment were observed. The grade of life quality about every patient was evaluated. Results Myelosuppression and the occurrence of nausea and vomitting in treatment group was obviously lower than control group (P ＜ 0.05). The proportion of improvement and stabilization for the quality of life in treatment group was markedly higher than control group (P ＜ 0.05). Conclusion Traditional Chinese drug Tianzhicao capsule had attenuation and synergy to postoperative chemotherapy in breast cancer.