CAJ | 학술논문

目的探讨18F-FDG PET/CT在可疑复发性宫颈癌临床诊疗中的价值.方法回顾性分析51例宫颈癌根治后随访期间临床可疑复发的患者,记录患者的治疗资料、可疑复发表现、18F-FDG PET/CT显像结果、同期常规影像检查结果、病理及临床随访结果、PET/CT结果对临床诊疗的影响.结果 PET/CT诊断宫颈癌复发43例,最终经病理检查及临床随访证实复发性宫颈癌40例,盆腔脓肿2例,放射性肠炎1例;PET/CT未见恶性征象8例,病理检查及临床随访均未见异常.PET/CT诊断复发性宫颈癌灵敏度为100.00%(40/40),特异性为72.73%(8/11),准确性为94.12%(48/51).PET/CT指导制订临床诊疗及随访计划34例,改变治疗计划7例.与其他影像检查相比,PET/CT可发现更多的病灶.结论 18F-FDG PET/CT能有效诊断复发性宫颈癌,指导临床诊疗.
목적 탐토18F-FDG PET/CT재가의복발성궁경암림상진료중적개치.방법 회고성분석51례궁경암근치후수방기간림상가의복발적환자,기록환자적치료자료、가의복발표현、18F-FDG PET/CT현상결과、동기상규영상검사결과、병리급림상수방결과、PET/CT결과대림상진료적영향.결과 PET/CT진단궁경암복발43례,최종경병리검사급림상수방증실복발성궁경암40례,분강농종2례,방사성장염1례;PET/CT미견악성정상8례,병리검사급림상수방균미견이상.PET/CT진단복발성궁경암령민도위100.00%(40/40),특이성위72.73%(8/11),준학성위94.12%(48/51).PET/CT지도제정림상진료급수방계화34례,개변치료계화7례.여기타영상검사상비,PET/CT가발현경다적병조.결론 18F-FDG PET/CT능유효진단복발성궁경암,지도림상진료.
Objective To evaluate the clinical impact of 18F-FDG PET/CT on patients with suspected cervical cancer recurrence. Methods Fifty-one cervical cancer patients, clinically suspected to have tumor recurrence during follow-up, underwent 18F-FDG PET/CT examination. 18 F-FDG PET/CT results were compared with those of conventional images, as referred to histopathology or clinical follow-up. Impacts of 18F-FDG PET/CT were evaluated based on documented changes of clinical management. Results In total, 43 patients were found to have positive lesions by 18F-FDG PET/CT, in which 40 were true recurrence,but 2 were pelvic abscess and 1 was radiation enterocolitis. Other 8 patients were found negative by 18F-FDG PET/CT and confirmed by pathology or follow-up. In patient-based analyses, the sensitivity, specificity, and accuracy of 18F-FDG PET/CT for the detection of tumor recurrence were 100% (40/40), 72. 73% (8/11),and 94.12% (48/51) respectively. In 7 patients, the clinical management was changed due to 18F-FDG PET/CT findings. Conclusion 18F-FDG PET/CT is an efficient tool for determining the recurrence of cervical cancer and instructing the clinical management.