中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2009年
20期
21,28
,共2页
益气活血颗粒%原发性高血压%醛固酮%血管紧张素Ⅱ
益氣活血顆粒%原髮性高血壓%醛固酮%血管緊張素Ⅱ
익기활혈과립%원발성고혈압%철고동%혈관긴장소Ⅱ
Yiqihuoxue granula%Essential hypertension%Aldosterone%Angiotensin Ⅱ
目的 观察益气活血颗粒对原发性高血压患者血浆醛固酮、血管紧张素Ⅱ浓度的影响,并探讨其作用机制.方法 将200例原发性高血压患者随机分为两组,常规降压组100例,给予常规降压治疗;联合治疗组100例,在常规降压治疗基础上加益气活血颗粒治疗,疗程均为4个月.分别检测治疗前后患者血压及血液中醛固酮(ALD)、血管紧张素Ⅱ(AngⅡ)的浓度.结果 益气活血颗粒能有效降低血压及循环血液中ADL、AngⅡ的浓度.结论 益气活血颗粒具有降低血压和抑制肾素-血管紧张素-醛固酮系统(RAAS)活性.
目的 觀察益氣活血顆粒對原髮性高血壓患者血漿醛固酮、血管緊張素Ⅱ濃度的影響,併探討其作用機製.方法 將200例原髮性高血壓患者隨機分為兩組,常規降壓組100例,給予常規降壓治療;聯閤治療組100例,在常規降壓治療基礎上加益氣活血顆粒治療,療程均為4箇月.分彆檢測治療前後患者血壓及血液中醛固酮(ALD)、血管緊張素Ⅱ(AngⅡ)的濃度.結果 益氣活血顆粒能有效降低血壓及循環血液中ADL、AngⅡ的濃度.結論 益氣活血顆粒具有降低血壓和抑製腎素-血管緊張素-醛固酮繫統(RAAS)活性.
목적 관찰익기활혈과립대원발성고혈압환자혈장철고동、혈관긴장소Ⅱ농도적영향,병탐토기작용궤제.방법 장200례원발성고혈압환자수궤분위량조,상규강압조100례,급여상규강압치료;연합치료조100례,재상규강압치료기출상가익기활혈과립치료,료정균위4개월.분별검측치료전후환자혈압급혈액중철고동(ALD)、혈관긴장소Ⅱ(AngⅡ)적농도.결과 익기활혈과립능유효강저혈압급순배혈액중ADL、AngⅡ적농도.결론 익기활혈과립구유강저혈압화억제신소-혈관긴장소-철고동계통(RAAS)활성.
Objective To investigate the effects of yiqihuoxue granula on the concentration of aldosterone(ALD) and angiotensin (Ang Ⅱ) of plasma in essential hypertension patients,and further study the mechanism of yiqihuoxue granula on de-creasing blood pressure in essential hypertension patients. Methods Two hundred patients with essential hypertension were ran-domly divided into two groups:100 patients in group A were given routine therapy;other 100 patients in group B were given rou-tine therapy and yiqihuoxue granula. The concentration of aldosterone(ALD) and angiotensin Ⅱ(Ang Ⅱ) of plasma and myocardi-urn by radioimmunoassay. Results Yiqihuoxue granula could decrease blood pressure and concentration of aldosterone(ALD) and angiotensin Ⅱ(Ang Ⅱ) of plasma in essential hypertension patients after 4 months treatment(P<0.05). Conclusions Yiqi-huoxue granula could restrain RAAS activity,which could be the mechanism of yiqihuoxue granula decrease blood pressure.
