中草药
中草藥
중초약
CHINESE TRADITIONAL AND HERBAL DRUGS
2004年
6期
611-614
,共4页
王环%张晓峰%马云保%蔡祥海%吴大刚%罗晓东
王環%張曉峰%馬雲保%蔡祥海%吳大剛%囉曉東
왕배%장효봉%마운보%채상해%오대강%라효동
大果大戟%大戟属%千金二萜烷型%松香烷型%对映-阿替斯烷型
大果大戟%大戟屬%韆金二萜烷型%鬆香烷型%對映-阿替斯烷型
대과대극%대극속%천금이첩완형%송향완형%대영-아체사완형
Euphorbia wallichii Hook.f.%Euphorbia L.%lathyrane%abietane%ent-atisane
目的研究大果大戟Euphorbia wallichii的化学成分.方法采用反复硅胶柱色谱分离纯化,通过波谱方法鉴定化合物结构.结果从大果大戟根部的乙醇提取物中分离得到9个二萜化合物,其中jolkinol B(Ⅰ)是千金二萜烷型;caudicifolin(Ⅱ),helioscopinolides A(Ⅲ),C(Ⅳ)和E(Ⅴ)是松香烷型;ent-atisane-3β,16α,17-triol(Ⅵ1),ent-16α,17-dihydroxyatisan-3-one(Ⅶ),ent-3β,(13S)-dihydroxyatis-16-en-14-one(Ⅷ)和ent-2-hydrox-yatis-1,16(17)-dien-3,14-dione(Ⅸ)属于对映-阿替斯烷型.结论这些成分均为首次从该植物中分离得到.
目的研究大果大戟Euphorbia wallichii的化學成分.方法採用反複硅膠柱色譜分離純化,通過波譜方法鑒定化閤物結構.結果從大果大戟根部的乙醇提取物中分離得到9箇二萜化閤物,其中jolkinol B(Ⅰ)是韆金二萜烷型;caudicifolin(Ⅱ),helioscopinolides A(Ⅲ),C(Ⅳ)和E(Ⅴ)是鬆香烷型;ent-atisane-3β,16α,17-triol(Ⅵ1),ent-16α,17-dihydroxyatisan-3-one(Ⅶ),ent-3β,(13S)-dihydroxyatis-16-en-14-one(Ⅷ)和ent-2-hydrox-yatis-1,16(17)-dien-3,14-dione(Ⅸ)屬于對映-阿替斯烷型.結論這些成分均為首次從該植物中分離得到.
목적연구대과대극Euphorbia wallichii적화학성분.방법채용반복규효주색보분리순화,통과파보방법감정화합물결구.결과종대과대극근부적을순제취물중분리득도9개이첩화합물,기중jolkinol B(Ⅰ)시천금이첩완형;caudicifolin(Ⅱ),helioscopinolides A(Ⅲ),C(Ⅳ)화E(Ⅴ)시송향완형;ent-atisane-3β,16α,17-triol(Ⅵ1),ent-16α,17-dihydroxyatisan-3-one(Ⅶ),ent-3β,(13S)-dihydroxyatis-16-en-14-one(Ⅷ)화ent-2-hydrox-yatis-1,16(17)-dien-3,14-dione(Ⅸ)속우대영-아체사완형.결론저사성분균위수차종해식물중분리득도.
Object To study the chemical constituents of Euphorbia wallichii.Methods The constituents were repeatedly separated and purified on silica gel column.They were identified on the basis of spectral methods.Results Nine diterpenoids were obtained from the roots of E. wallichii.Among them jolkinol B(I) is lathyrane type;caudicifolin (Ⅱ),helioscopinolides A(Ⅲ),C(Ⅳ),and E(Ⅴ) belong to abietane type;while ent-atisane-3β,16α,17-triol(Ⅵ),ent-16α,17-dihydroxyatisan-3-one(Ⅶ),ent-3β,(13S)-dihydroxyatis-16-en-14-one(Ⅷ),and ent-2-hydroxy-atis-1,16(17)-dien-3,14-dione(Ⅸ) possess an ent-atisane skeleon.Conclusion All of them are isolated from E. wallichii for the first time.
