CAJ | 학술논문

目的探讨川芎嗪联合依那普利治疗早期糖尿病肾病的疗效及安全性.方法将本院120例早期DN患者随机分为治疗组及对照组,对照组采用常规治疗,治疗组在对照组基础上加用川芎嗪和依那普利.结果治疗组的总有效率93.3%,显著高于对照组的75.0%,差异有统计学意义(P<0.05),两组均未见出血、皮疹及呼吸困难病例.结论川芎嗪与依那普利联用治疗早期DN,能起相互协同增效作用,防止DN的进一步恶化,值得临床推广应用.
목적 탐토천궁진연합의나보리치료조기당뇨병신병적료효급안전성.방법 장본원120례조기DN환자수궤분위치료조급대조조,대조조채용상규치료,치료조재대조조기출상가용천궁진화의나보리.결과 치료조적총유효솔93.3%,현저고우대조조적75.0%,차이유통계학의의(P<0.05),량조균미견출혈、피진급호흡곤난병례.결론 천궁진여의나보리련용치료조기DN,능기상호협동증효작용,방지DN적진일보악화,치득림상추엄응용.
Objective Discuss ligustrazine joint enalapril treatment early diabetic nephropathy efficacy and safety. Methods 120 cases of early DN were randomly divided into treatment group and control group in our hospital, control group were treatment conventional,treatment group added to take ligustrazine and enalapril. Results treatment group total effective rate was 93.3%, significantly higher than treatment group's 75.0%, there were significant differences(P<0.05), two groups were no bleeding, skin rashes and breathing difficulties in case. Conclusion Ligustrazine joint enalapril treatment early diabetic nephropathy, can play each other synergies, prevent DN further deterioration, Worthy clinical application.