CAJ | 학술논문

考察Fire-Diffuse-Fire模型在圆柱区域内钙波的传播情况.通过求解扩散方程,得到了圆柱区域内Ca~(2+)浓度的解析表达式.分析证明了钙波的存在性、稳定性依赖于半径和Ca~(2+)泵率,产生钙释放的阈值在有限区间内随半径增大而增大.此结果有助于了解细胞内的内质网以及Ca~(2+)泵在细胞Ca~(2+)动力学上的作用.
고찰Fire-Diffuse-Fire모형재원주구역내개파적전파정황.통과구해확산방정,득도료원주구역내Ca~(2+)농도적해석표체식.분석증명료개파적존재성、은정성의뢰우반경화Ca~(2+)빙솔,산생개석방적역치재유한구간내수반경증대이증대.차결과유조우료해세포내적내질망이급Ca~(2+)빙재세포Ca~(2+)동역학상적작용.
Propagation of fire-diffuse-fire Ca~(2+) waves through a cylindric domain is considered.Ca~(2+) concentration is an analytic solution derived from the diffusion equation in the domain.Existence and stability are shown to be dependent on the radius and the Ca~(2+) pump rate.It is also shown that the threshold of fire increase as radius increasing in finite interval.The results provides better understanding about the roles of endoplasmic and Ca~(2+) pumps in the intracellular Ca~(2+) dynamics of cells.