畜牧与生物技术杂志(英文版)
畜牧與生物技術雜誌(英文版)
축목여생물기술잡지(영문판)
JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY
2012年
2期
60-67
,共8页
miRNA%Bovine%Beef tenderness%Stress
miRNAs are a class of small,single-stranded,non-coding RNAs that perform post-transcriptional repression of target genes by binding to 3' untranslated regions.Research has found that miRNAs involved in the regulation of many metabolic processes.Here we uncovered that the beef quality of Angus cattle sharply diversified after acute stress.By performing miRNA microarray analysis,13 miRNAs were significantly differentially expressed in stressed group compared to control group.Using a bioinformatics method,135 protein-coding genes were predicted as the targets of significant differentially expressed miRNAs.Gene Ontology (GO) term and Ingenuity Pathway Analysis (IPA) mined that these target genes involved in some important pathways,which may have impact on meat quality and beef tenderness.