CAJ | 학술논문

目的探讨近视青少年黄斑厚度和黄斑容积的变异程度与等效球镜、眼轴长度、性别、年龄、及眼别的关系.方法横断面调查研究.应用Stratus相干光断层扫描(OCT)仪的黄斑快速扫描程序用直径为6mm的相邻30°的6条扫描线,测量154例(154只眼)7～18岁近视青少年的黄斑中心小凹、中心区和旁中心凹内、外环(直径分别为1、3、6mm)的颞、上、鼻、下各个区域的厚度和容积,并用A超测定眼轴长度.各影响因素与黄斑各区域的厚度和容积分别进行双变量直线回归分析.结果黄斑旁中心凹上方和鼻侧较下方和颞侧厚.黄斑中心凹最薄处厚度、黄斑中心区厚度和容积与等效球镜、眼轴长度、性别、年龄、及眼别均无关(P>0.05);黄斑区总容积与等效球镜度数呈正相关(r=0.273,P=0.001),与眼轴长度呈负相关(r=0.285,P=0.001);内环和外环各方位厚度及容积与等效球镜均呈正相关(P<0.05):眼轴长度与内环下方和外环各方位厚度和容积呈负相关(P<0.05);年龄与内环鼻、颞侧、外环鼻侧厚度和容积呈正相关(P<0.05);性别与外环下方厚度和容积呈负相关(P<0.05);眼别与黄斑各区域厚度和容积均无关(P>0.05).结论随着近视程度和眼轴长度的增加,青少年黄斑部变薄的区域在旁中心凹区而不是中心区.在评价青少年黄斑厚度和黄斑容积时,需考虑其近视程度、眼轴长度、年龄及性别的影响.
목적 탐토근시청소년황반후도화황반용적적변이정도여등효구경、안축장도、성별、년령、급안별적관계.방법 횡단면조사연구.응용Stratus상간광단층소묘(OCT)의적황반쾌속소묘정서용직경위6mm적상린30°적6조소묘선,측량154례(154지안)7～18세근시청소년적황반중심소요、중심구화방중심요내、외배(직경분별위1、3、6mm)적섭、상、비、하각개구역적후도화용적,병용A초측정안축장도.각영향인소여황반각구역적후도화용적분별진행쌍변량직선회귀분석.결과 황반방중심요상방화비측교하방화섭측후.황반중심요최박처후도、황반중심구후도화용적여등효구경、안축장도、성별、년령、급안별균무관(P>0.05);황반구총용적여등효구경도수정정상관(r=0.273,P=0.001),여안축장도정부상관(r=0.285,P=0.001);내배화외배각방위후도급용적여등효구경균정정상관(P<0.05):안축장도여내배하방화외배각방위후도화용적정부상관(P<0.05);년령여내배비、섭측、외배비측후도화용적정정상관(P<0.05);성별여외배하방후도화용적정부상관(P<0.05);안별여황반각구역후도화용적균무관(P>0.05).결론 수착근시정도화안축장도적증가,청소년황반부변박적구역재방중심요구이불시중심구.재평개청소년황반후도화황반용적시,수고필기근시정도、안축장도、년령급성별적영향.
Objective To evaluate the associations between macular thickness and volume, assessed by optic coherence tomography (OCT), with spherical equivalent (SE), axial length (AL), gender, age, eye in myopic juvenile.Methods Cross-sectional observational study.One hundred and fifty-four juvenile (age range, 7-18 years) underwent ophthalmic examination.Fast macular scans were performed by Stratus OCT with six 6-mm lines (oriented 30° apart) in a radial spokelike pattern on one randomly selected eye of each subject.Average macular thickness and macular volume was provided for each of the nine regions with outer radii for the central, inner, and outer macular regions being 1, 3 and 6mm, respectively.AL was respectively measured by A-ultrasound.The effects of several factors (SE, AL, gender, age, and eye) on macular thickness and volume were investigated in univariate analyses.Results The retina was thicker at the superior and nasal parafovea compared to the inferior or temporal parafovea.The mean minimum retinal thickness (at the foveola), the central macular thickness and volume had no significant relationship between SE, AL, gender, age and eye (P >0.05).The total macular volume showed direct linear correlation with SE (r=0.273, P =0.001), and inverse linear correlation with AL (r=-0.285, P =0.001).There was significant direct linear correlation between SE and the thickness and volume of inner and outer macula (P<0.05).AL showed inverse linear correlation with the thickness and volume of inferior inner macula and outer macula (P <0.05).Age showed direct linear correlation between the thickness and volume of nasal inner macula, temporal inner macula, nasal outer macula (P <0.05).There was significant inverse linear correlation between the thickness and volume of inferior outer macula and gender (P<0.05).Macula thickness and volume was not significantly related to the laterality.Conclusions As the AL and the myopic degree of eye increase, the macula thickness and volume decrease at the parafovea, instead of the fovela.When we asses the macular sthickness and volume in myopic juvenile.we should consider the inflnence of the refraction.axial length eye.