CAJ | 학술논문

目的寻找适用于胃癌术后患者预后比较的简单指标.方法选取1999-2005年间在复旦大学附属中山医院胃肿瘤组接受根治性手术治疗的148例患者的病例资料进行总结,分析胃周淋巴结转移情况及其与患者预后的关系.结果 148例患者3年累计总生存率为62.8%,生存率随胃周转移淋巴结数增加而下降,当胃周转移淋巴结数超过6枚时,3年生存率降至15.4%,与全组3年总生存率比较,差异有统计学意义(P<0.01).胃周转移淋巴结数与总阳性淋巴结数存在线性关系(r=0.94,P<0.01),但与总切除淋巴结数不存在线性关系(r=0.18,P=0.2).结论胃周转移淋巴结是一个简单有效判断胃癌术后患者预后的指标.胃周转移淋巴结对淋巴结切除技术要求低,可用于比较不同地区间胃癌术后患者的预后.
목적 심조괄용우위암술후환자예후비교적간단지표.방법 선취1999-2005년간재복단대학부속중산의원위종류조접수근치성수술치료적148례환자적병례자료진행총결,분석위주림파결전이정황급기여환자예후적관계.결과 148례환자3년루계총생존솔위62.8%,생존솔수위주전이림파결수증가이하강,당위주전이림파결수초과6매시,3년생존솔강지15.4%,여전조3년총생존솔비교,차이유통계학의의(P<0.01).위주전이림파결수여총양성림파결수존재선성관계(r=0.94,P<0.01),단여총절제림파결수불존재선성관계(r=0.18,P=0.2).결론 위주전이림파결시일개간단유효판단위암술후환자예후적지표.위주전이림파결대림파결절제기술요구저,가용우비교불동지구간위암술후환자적예후.
Objective To find out a simple and reprodctive prognostic index in gastric cancer patients, which can be used as a comparable parameter among different regions of China. Methods The perigastric metastatic lymph nodes (PGMLN) with long-term survival data were retrospectively evaluated in 148 gastric cancer patients, undergone potentially curative resections. Results The 3-year cumulative survival rate was 62.8% and the survival rate decreased significantly with the increase of PGMLN, especially when the PGMLN was more than 6. The PGMLN had a clear linear relationship with total positive lymph nodes (r=0.94, P<0.01), while it had little correlation with total resected lymph nodes (r=0.18,P=0.2). Conclusions PGMLN is a convenient and reliable prognostic factor in gastric cancer patients, which may be a good candidate of comparable parameters among different regions of China.