CAJ | 학술논문

目的:探讨组织细胞坏死性淋巴结炎的临床特点.方法:回顾性分析11例组织细胞坏死性淋巴结炎的临床表现、淋巴结活检病理学特点及其诊治.结果:所有患者均有颈部淋巴结肿大和持续性发热,大多数患者白细胞减少、血沉增快.11例患者均由颈部淋巴结活检确诊.淋巴结活检病理学特点为不同程度的凝固性坏死伴多种形态的组织细胞、淋巴细胞浸润,无中性粒细胞浸润.应用疗程为2～4个月的肾上腺皮质激素治疗,疗效显著,未复发.结论:组织细胞坏死性淋巴结炎的临床表现无特异性,较易误诊,确诊主要依靠淋巴结活检.
목적:탐토조직세포배사성림파결염적림상특점.방법:회고성분석11례조직세포배사성림파결염적림상표현、림파결활검병이학특점급기진치.결과:소유환자균유경부림파결종대화지속성발열,대다수환자백세포감소、혈침증쾌.11례환자균유경부림파결활검학진.림파결활검병이학특점위불동정도적응고성배사반다충형태적조직세포、림파세포침윤,무중성립세포침윤.응용료정위2～4개월적신상선피질격소치료,료효현저,미복발.결론:조직세포배사성림파결염적림상표현무특이성,교역오진,학진주요의고림파결활검.
Objective:To study the clinical features of histiocytic necrotizing lymphadenitis. Method: Eleven pa-tients with histiocytic necrotizing lymphadenitis were collected to analyze the clinical features, pathological features of biopsy lymph nodes,diagnosis and treatment. Result:Lymph node swelling of neck and persistent fever were de-tected in all patients. The leukocyte reduction and swiftness of ESR in serum were detected in most patients. The final diagnosis of histiocytic necrotizing lymphadenitis was confirmed by biopsy investigation of the pathology. The pathological features included distinctive necrosis, loss of lymph node structure, infiltration with histiocytes and lymphocytes, absence of neutrophils. All patients were treated with glucocorticoid for 2 to 4 months. The patients improved significantly and were not recurrence during follow up visit. Conclusion: There was no specific clinical manifestation of histiocytic necrotizing lymphadenitis and which easy to misdiagnose. Diagnosis of histiocytic ne-crotizing lymphadenitis relies on the pathological examination of enlarged lymph nodes.