CAJ | 학술논문

目的观察左卡尼汀联合疏血通治疗慢性肾功能衰竭的临床疗效及安全性.方法 94例慢性肾功能衰竭患者按随机原则分为A组和B组各47例,A组采用左卡尼汀联合疏血通治疗,B组采用疏血通治疗.观察两组治疗总有效率、不良反应发生率及血清尿素氮、肌酐、高半胱氨酸水平.结果两组治疗30 d后,A组治疗总有效率高于B组(P＜0.05),A、B两组不良反应发生率差异无统计学意义(P＞0.05).血清尿素氮、肌酐、高半胱氨酸水平治疗后A组与B组比较,差异均有统计学意义(均P＜0.05).结论在慢性肾功能衰竭患者中采用左卡尼丁联合疏血通治疗效果明显,不良反应少.
목적 관찰좌잡니정연합소혈통치료만성신공능쇠갈적림상료효급안전성.방법 94례만성신공능쇠갈환자안수궤원칙분위A조화B조각47례,A조채용좌잡니정연합소혈통치료,B조채용소혈통치료.관찰량조치료총유효솔、불량반응발생솔급혈청뇨소담、기항、고반광안산수평.결과 량조치료30 d후,A조치료총유효솔고우B조(P＜0.05),A、B량조불량반응발생솔차이무통계학의의(P＞0.05).혈청뇨소담、기항、고반광안산수평치료후A조여B조비교,차이균유통계학의의(균P＜0.05).결론 재만성신공능쇠갈환자중채용좌잡니정연합소혈통치료효과명현,불량반응소.
Objective To study the effects and safety of levocarnitine and shuxuetong in treatment of the patients with chronic renal failure.Methods 94 patients with chronic renal failure were selected as research object,and they were randomly divided into group A(levocarnitine and shuxuetong group) 47 cases and group B(shuxuetong group) 47 cases.Group A were treated with levocarnitine oral solution and shuxuetong,and group B were treated with shuxuetong,then the percentage of effectiveness,incidence of adverse reactions of group A and group B and serum BUN,Scr,Hcy were analyzed.Results The percentage of effectiveness of group A was higher than that of group B,but the incidence of adverse reactions of the two groups had no difference,and the serum BUN,Scr,Hcy of group A and group B before the treatment had no differences(P＞0.05),those of group A and group B after treatment were compared there were significant differences(all P＜0.05).Conclusion The effects of levocarnitine oral solution and shuxuetong in treatment of patients with chronic renal failure were better.