CAJ | 학술논문

为探讨微量元素与甲肿病间的关联性及临床意义。采用ICP-AES等离子体发射光谱仪和2,3-二氨基萘荧光法测定楚雄地区甲肿患者人发中12种微量元素。选取甲肿病患者30例,对照组33例。结果表明,甲肿组发中Zn、Cu、Mn、N i、Se、Sr、P水平降低,Cd、Cr、Fe、Mg、Ca水平升高,并有显著差异（P〈0.05）。甲肿病组间性别比较显示男性发Mn、N i高于女性,发Fe水平差异不大,其余元素含量均低于女性。中年组发Zn、Cd、Cr、Cu、N i、Sr、Mg、Ca水平较高,青年组发Se、Fe、Mn、P等元素含量较高。城市人群发Cu、Sr、Se、Mg、Ca含量比农村人群高（P〈0.05）,其余均低于农村人群。微量元素与甲状腺功能状态相互关联,在甲肿的病理生理机制中可能起着重要作用。
위탐토미량원소여갑종병간적관련성급림상의의。채용ICP-AES등리자체발사광보의화2,3-이안기내형광법측정초웅지구갑종환자인발중12충미량원소。선취갑종병환자30례,대조조33례。결과표명,갑종조발중Zn、Cu、Mn、N i、Se、Sr、P수평강저,Cd、Cr、Fe、Mg、Ca수평승고,병유현저차이（P〈0.05）。갑종병조간성별비교현시남성발Mn、N i고우녀성,발Fe수평차이불대,기여원소함량균저우녀성。중년조발Zn、Cd、Cr、Cu、N i、Sr、Mg、Ca수평교고,청년조발Se、Fe、Mn、P등원소함량교고。성시인군발Cu、Sr、Se、Mg、Ca함량비농촌인군고（P〈0.05）,기여균저우농촌인군。미량원소여갑상선공능상태상호관련,재갑종적병리생리궤제중가능기착중요작용。
To analysis of the mineral elements and its clinical significance in endemic goiter.the contents of 12 trace elements in endemic goitrous patient＇s hair in Chuxiong were determined with ICP-AES spectroflaorimetry and 2,3-2 Naphthylamine.The hair samples of 30 patients and 33 healthy volunteers were diagnosed.The results show that the contents of Zn,Cu,Mn,Ni,Se,Sr and P in goitrous patient group are lower than those in healthy people,and Cd,Cr,Fe,Mg and Ca higher,with much difference（P0.05）.It is also showed that,in the goitrous patient group,the contents of Mn and Ni in the female hair are higher than those in the male,with no difference in the contents of Fe,and the contents of other trace elements are lower in the male.The contents of Zn,Cd,Cr,Cu,Ni,Sr,Mg and Ca are much higher in the middle aged goitrous patient＇s hair,and the contents of Se,Fe,Mn and P are also much higher in the young goitrous patient＇s hair.The contents of Cu,Sr,Se,Mg and Ca in the people＇s hair in the urban area are higher than those in the rural;however,the contents of the other trace elements are much lower.The contents of trace elements,which may cause goiter,are closely related to thyroid function.