CAJ | 학술논문

MicroRNA(miRNA)是一类大小约21～23个碱基的单链小分子非编码RNA,能够通过与靶mRNA特异性的碱基互补配对引起靶mRNA的降解或者抑制其翻译,从而对基因进行转录后表达调控.miRNAs广泛存在于动物、植物、细菌、病毒等多种生物物种中,并广泛参与了时空发育调控、细胞凋亡、肿瘤、病原体感染等多种生物学进程.近年来在昆虫研究领域,分别对不同昆虫物种的miRNA进行了鉴定与研究,该文对其研究进展作一综述.
MicroRNA(miRNA)시일류대소약21～23개감기적단련소분자비편마RNA,능구통과여파mRNA특이성적감기호보배대인기파mRNA적강해혹자억제기번역,종이대기인진행전록후표체조공.miRNAs엄범존재우동물、식물、세균、병독등다충생물물충중,병엄범삼여료시공발육조공、세포조망、종류、병원체감염등다충생물학진정.근년래재곤충연구영역,분별대불동곤충물충적miRNA진행료감정여연구,해문대기연구진전작일종술.
MicroRNAs (miRNAs) are non-coding 21-23 nt RNAs that play important gene-regulatory roles in animals and plants. Through specific base-pairing with mRNAs, these tiny RNAs induce mRNA degradation or translational repression, or both. MiRNAs are widely distributed in various species, including animals, plants, viruses etc. , miRNAs are involved in comprehensive biological processes such as spatio-temporal regulation of development, apoptosis, cancer, viral infection etc.. MiRNAs in different insect species were identified and studied in recent years. The present paper reviews the advanced researches on miRNA in insects.