药学学报
藥學學報
약학학보
ACTA PHARMACEUTICA SINICA
2008年
9期
934-937
,共4页
何仰清%马占营%杨谦%姚秉华%高黎明
何仰清%馬佔營%楊謙%姚秉華%高黎明
하앙청%마점영%양겸%요병화%고려명
太白乌头%二萜生物碱%isodelelatine
太白烏頭%二萜生物堿%isodelelatine
태백오두%이첩생물감%isodelelatine
Aconitum taipaicum%diterpene alkaloid%isodelelatine
为了研究太白乌头(Aconitum taipaicum)根的化学成分,采用硅胶柱色谱进行分离纯化,根据其理化性质和波谱数据确定化合物结构.从该植物的根中分离得到1个新的去甲二萜生物碱isodelelatine(1)和5个已知生物碱,分别为atisine(2)、delfissinol(3)、liangshanine(4)、hypaconitine(5)和delelatine(6).化合物2-6均为首次从该植物中分离得到.
為瞭研究太白烏頭(Aconitum taipaicum)根的化學成分,採用硅膠柱色譜進行分離純化,根據其理化性質和波譜數據確定化閤物結構.從該植物的根中分離得到1箇新的去甲二萜生物堿isodelelatine(1)和5箇已知生物堿,分彆為atisine(2)、delfissinol(3)、liangshanine(4)、hypaconitine(5)和delelatine(6).化閤物2-6均為首次從該植物中分離得到.
위료연구태백오두(Aconitum taipaicum)근적화학성분,채용규효주색보진행분리순화,근거기이화성질화파보수거학정화합물결구.종해식물적근중분리득도1개신적거갑이첩생물감isodelelatine(1)화5개이지생물감,분별위atisine(2)、delfissinol(3)、liangshanine(4)、hypaconitine(5)화delelatine(6).화합물2-6균위수차종해식물중분리득도.
To investigate the chemical constituents of the roots of Aconitum taipaicum, silica gel column chromatography was used for the isolation and purification of compounds. A new norditerpenoid alkaloid, isodelelatine (1), along with five known alkaloids, atisine (2), delfissinol (3), liangshanine(4), hypaconitine (5) and delelatine (6) were isolated and identified. The structure of the new compound was elucidated on the basis of spectral data.