中国人民解放军军医大学学报
中國人民解放軍軍醫大學學報
중국인민해방군군의대학학보
JOURNAL OF MEDICAL COLLEGES OF PLA
2004年
4期
201-204
,共4页
秦建民%刘淑琴%曾锦章%李慎菁%付晓勇%邱秀华%吴孟超%王红阳
秦建民%劉淑琴%曾錦章%李慎菁%付曉勇%邱秀華%吳孟超%王紅暘
진건민%류숙금%증금장%리신정%부효용%구수화%오맹초%왕홍양
mouse%embryogenesis%Gankyrin%gene expression
Objective: To observe the gene expression of Gankyrin during mouse embryogenesis and reveal the gene biological significance during organs and tissues formation. Methods: The expressions of Gankyrin mRNA in various organs and tissues were detected by in situ hybridization at indicated times during embryogenesis. Results: The expression of Gankyrin mRNA in mouse day 12.5 embryo was mainly in midbrain, interbrain and endbrain; in mouse day 14.5 embryo mainly in midbrain, aorta, liver, gonad, cranium and rib; in mouse day 16.5 embryo mainly in cranium, rib and vertebra;and in mouse day 18.5 embryo mainly in cranium, rib and intestinal mucosa. Conclusion: Gankyrin gene probably participates in the development of the neural tissues (such as midbrain, interbrain and endbrain etc. ), aorta, liver and gonad, intestinal mucosa and bone tissues, which may be closely associated with the function of the organs and tissues.
