糖尿病合并大血管病变的危险性研究--4845例糖尿病患者合并慢性并发症及治疗现状调查
당뇨병합병대혈관병변적위험성연구--4845례당뇨병환자합병만성병발증급치료현상조사
A survey on the diabetic macrovascular complications and related risk factors in the 4845 Chinese diabetic patients
  • 万方数据
    中国糖尿病杂志 중국당뇨병잡지
    CHINESE JOURNAL OF DIABETES
    2006年 3期 197-200 ,共4页

    王玉珍%赵德明%许樟荣%伍春荣%敬华%刘彦君%余红亚%胡莲娜%倪彩红%宋晓菲%杨乐冰%王爱红%杨文生%杨晋德

    왕옥진%조덕명%허장영%오춘영%경화%류언군%여홍아%호련나%예채홍%송효비%양악빙%왕애홍%양문생%양진덕

    糖尿病%并发症%大血管%微血管%肥胖 糖尿病%併髮癥%大血管%微血管%肥胖
    당뇨병%병발증%대혈관%미혈관%비반
    Diabetes mellitus%Complications% Macrovascular% Microvascular% Obesity
    目的调查和分析糖尿病患者合并慢性并发症和治疗现状以及采用1997年ADA糖尿病诊断标准前后5年的糖尿病大血管危险因素的变化.方法分析1993～2003年期间参与糖尿病并发症筛查的4845名患者资料,并比较了1993～1997年(A组)和1998～2003年(B组)两个时间段筛查患者的糖尿病并发症和体重、血压以及血糖等变化. 结果60.5%的患者HbA1c超过8.5%;近一半的患者治疗的依从性比较差或差;38.3%的患者合并心、脑和(或)下肢血管病变病;2.0%的患者有足(趾)坏疽;54.5%的患者合并高血压.B组与A组比较,视网膜病变、体位性低血压、心率大于90次/min、Cr＞133μmo1/L的患者比例及高血压的检出率明显减少;BMI大于28kg/m2的比例由18%增加至26%、腰围由86±10 cm增加至88±10 cm. 结论糖尿病合并大血管危险因素应该受到高度重视.
    목적조사화분석당뇨병환자합병만성병발증화치료현상이급채용1997년ADA당뇨병진단표준전후5년적당뇨병대혈관위험인소적변화.방법분석1993～2003년기간삼여당뇨병병발증사사적4845명환자자료,병비교료1993～1997년(A조)화1998～2003년(B조)량개시간단사사환자적당뇨병병발증화체중、혈압이급혈당등변화. 결과60.5%적환자HbA1c초과8.5%;근일반적환자치료적의종성비교차혹차;38.3%적환자합병심、뇌화(혹)하지혈관병변병;2.0%적환자유족(지)배저;54.5%적환자합병고혈압.B조여A조비교,시망막병변、체위성저혈압、심솔대우90차/min、Cr＞133μmo1/L적환자비례급고혈압적검출솔명현감소;BMI대우28kg/m2적비례유18%증가지26%、요위유86±10 cm증가지88±10 cm. 결론당뇨병합병대혈관위험인소응해수도고도중시.
    Objective To investigate the prevalence of diabetic macroangiopathy and its risk factors change before and after 1997-diabetes diagnostic criteria. Methods The 4845 patients were divided into two groups according to complication screening time: group A (1993~1997) and group B (1998~2003). Results The hyperglycemic treatment compliance was poor in nearly half of DM patients, including 17.5% of them out of diet control.12.4% were treated with insulin.There were patients with ischemic heart disease(31.9%), cerebral vascular disease(11.1%), un-palpabilities of dorsalis pedis pulse and/or posterior tibial pulse(26.3%), gangrene(2.0%), hypertension(54.5%).Group B showed lower detection rates of DN(6.1% vs 30.4%),postual hypotension (6.4% vs 22.9%), the increased seram creatinine (>133 μmol/L)(1.5% vs 3.0%), and HbA1c (8.4% vs 9.0%)(all P<0.01) as compared with group A, and showed the similar detection rates of DN (26.6% vs 25.4%), hypertension (36.9% vs 40.5%),tachycardia (15.6% vs 17%) to the group A.Group B had higher rate of central obesity (high WC) in both male (70.1% vs 60.8%) and female (72.5% vs 58.1%) versus group A(all P<0.01). Conclusions The patients screened for diabetic complications from 1998-2003 shows a lower blood glucose level,lower prevalence of microvascular complications, but more severe cluster of macrovascular risk factors.
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