中华急诊医学杂志
中華急診醫學雜誌
중화급진의학잡지
CHINESE JOURNAL OF EMERGENCY MEDICINE
2011年
10期
1089-1091
,共3页
急性脑梗死%ET-1%神经功能缺损%血糖%肌酐%尿素氮
急性腦梗死%ET-1%神經功能缺損%血糖%肌酐%尿素氮
급성뇌경사%ET-1%신경공능결손%혈당%기항%뇨소담
Acute cerebral infarction%ET-1%Neurologic impairment%Glucose%Creatinine%Urea nitrogen
目的 探讨急性脑梗死患者血糖、肌酐、尿素氮及血清内皮素( endothelin-1,ET-1)水平的变化及其神经功能缺损程度与ET-1水平的关系.方法 用125I放射免疫法分析50例发病在24h内的急性脑梗死患者与对照组50例同期非神经系统疾病患者血清ET-1水平的变化,并比较其血糖、肌酐及尿素氮水平.结果 急性脑梗死组血糖、肌酐及尿素氮水平差异无统计学意义(P＞0.05),但血清ET-1水平显著性高于对照组(P＜0.01),且急性脑梗死血清ET-1水平的变化与其神经功能缺损程度显著性相关,不同组间均P值＜0.01.结论 血清ET-1水平可作为急性脑梗死发生预测及预后评估的指标之一.
目的 探討急性腦梗死患者血糖、肌酐、尿素氮及血清內皮素( endothelin-1,ET-1)水平的變化及其神經功能缺損程度與ET-1水平的關繫.方法 用125I放射免疫法分析50例髮病在24h內的急性腦梗死患者與對照組50例同期非神經繫統疾病患者血清ET-1水平的變化,併比較其血糖、肌酐及尿素氮水平.結果 急性腦梗死組血糖、肌酐及尿素氮水平差異無統計學意義(P＞0.05),但血清ET-1水平顯著性高于對照組(P＜0.01),且急性腦梗死血清ET-1水平的變化與其神經功能缺損程度顯著性相關,不同組間均P值＜0.01.結論 血清ET-1水平可作為急性腦梗死髮生預測及預後評估的指標之一.
목적 탐토급성뇌경사환자혈당、기항、뇨소담급혈청내피소( endothelin-1,ET-1)수평적변화급기신경공능결손정도여ET-1수평적관계.방법 용125I방사면역법분석50례발병재24h내적급성뇌경사환자여대조조50례동기비신경계통질병환자혈청ET-1수평적변화,병비교기혈당、기항급뇨소담수평.결과 급성뇌경사조혈당、기항급뇨소담수평차이무통계학의의(P＞0.05),단혈청ET-1수평현저성고우대조조(P＜0.01),차급성뇌경사혈청ET-1수평적변화여기신경공능결손정도현저성상관,불동조간균P치＜0.01.결론 혈청ET-1수평가작위급성뇌경사발생예측급예후평고적지표지일.
Objective To study glucose,creatinine,urea nitrogen and serum ET-1 of patients with acute cerebral infarction,and to explore the relationship between neurologic impairment and ET-1 levels.Methods The glucose,creatinine,urea nitrogen and serum ET-1 were retrospectively analyzed in 50 patients with acute cerebral infarction ( ＜ 24 h) and 50 patients with non-neurological diseases.ET-1 determined by 125I radioimmunoassay.Results There were no significant differences in glucose,creatinine and urea nitrogen of acute cerebral infarction ( P ＞ 0.05 ) ; Compared to the control groups,ET-1 levels was significantly higher ( P ＜ 0.01 ),and levels of serum ET-1 in acute cerebral infarction were significantly correlated with their neurological deficits ( P ＜ 0.01 ).Conclusions Levels of serum ET-1 can severd as diagnostic and prognostic indicator of acute cerebral infarction.
