CAJ | 학술논문

目的探讨维持性血液透析患者动静脉内瘘(AVF)有效的保护方法.方法 85例维持性血液透析需行动静脉内瘘手术的患者随机分为2组,即潘生丁与罂粟碱联合治疗组(n=43),阿司匹林对照组(n=42),观察两组患者血管狭窄、血管闭塞、血管瘤样扩张、血管硬结的发生率及内瘘血流量、拔针后出血时间、动态静脉压、KT/V数值比较.结果治疗组43例中出现闭塞1例,占2.33％,血管狭窄6例,占13.95％,对照组42例中出现闭塞8例,占19.05％,血管狭窄15例,占35.71％,两组比较有统计学意义(P＜0.05)；治疗组与对照组内瘘血流量、拔针后出血时间、动态静脉压、KT/V比较均有统计学意义(P＜ 0.05).结论潘生丁联用罂粟碱可有效保护动静脉内瘘,并可延长AVF使用寿命.
목적 탐토유지성혈액투석환자동정맥내루(AVF)유효적보호방법.방법 85례유지성혈액투석수행동정맥내루수술적환자수궤분위2조,즉반생정여앵속감연합치료조(n=43),아사필림대조조(n=42),관찰량조환자혈관협착、혈관폐새、혈관류양확장、혈관경결적발생솔급내루혈류량、발침후출혈시간、동태정맥압、KT/V수치비교.결과 치료조43례중출현폐새1례,점2.33％,혈관협착6례,점13.95％,대조조42례중출현폐새8례,점19.05％,혈관협착15례,점35.71％,량조비교유통계학의의(P＜0.05)；치료조여대조조내루혈류량、발침후출혈시간、동태정맥압、KT/V비교균유통계학의의(P＜ 0.05).결론 반생정련용앵속감가유효보호동정맥내루,병가연장AVF사용수명.
Objective To investigate an effective method for protection of arteriovenous fistula ( AVF ) in patients on maintenance hemodialysis.Methods 85 patients on maintenance hemodialysis who required surgery for arteriovenous fistula were randomly divided into dipyridamole and narceine group ( n =43 ) and aspirin group ( n =42 ).The incidence rates of vascular stenosis, occlusion of blood vessels, vascular ectasia, and vascular sclerosis were observed.Volume of blood flow to fistula,bleeding time after needle removal,dynamic venous pressure,and KT/V values?? were compared.Results In dipyridamole and narceine group,occlusion of blood vessels occurred in one patient ( 2.33％ ) and vascular stenosis developed in 6 ( 13.95％ ); whereas in the control group,occlusion of blood vessels occurred in 8 patients ( 19.05％ ) and vascular stenosis developed in 15 ( 35.71％ ),with a significant statistical difference ( P＜ 0.05 ).There were significant differences in volume of blood flow to fistula,bleeding time after needle removal,dynamic venous pressure,and KT/V ( P＜ 0.05 ).Conclusions Dipyridamole combined with narceine can effectively protect internal arteriovenous fistula and prolong its lifespan.