CAJ | 학술논문

目的总结血液净化(blood purification,BP)治疗非肾脏疾病危重症患儿的经验.方法回顾性分析2009年1月至12月在我院PICU因非肾脏疾病而行BP治疗的10例危重症患儿的临床资料.10例患儿中,5例为急性肝能衰竭;2例自身免疫性疾病,其中1例吉兰-巴雷综合征,1例幼年特发性关节炎(全身型)并发MAS;2例重症脓毒症;1例由于代谢病出现持续性的严重代谢性酸中毒.结果 10例非肾脏疾病危重患儿中,实施CVVH联合PE治疗4例次,单纯CVVH治疗3例,单纯PE治疗3例.临床痊愈7例,好转1例,家长放弃2例.结论 BP作为一种脏器功能替代及支持的新疗法对PICU中肝功能衰竭及自身免疫性疾病等非肾脏病危重症患儿有较好的疗效.
목적 총결혈액정화(blood purification,BP)치료비신장질병위중증환인적경험.방법 회고성분석2009년1월지12월재아원PICU인비신장질병이행BP치료적10례위중증환인적림상자료.10례환인중,5례위급성간능쇠갈;2례자신면역성질병,기중1례길란-파뢰종합정,1례유년특발성관절염(전신형)병발MAS;2례중증농독증;1례유우대사병출현지속성적엄중대사성산중독.결과 10례비신장질병위중환인중,실시CVVH연합PE치료4례차,단순CVVH치료3례,단순PE치료3례.림상전유7례,호전1례,가장방기2례.결론 BP작위일충장기공능체대급지지적신요법대PICU중간공능쇠갈급자신면역성질병등비신장병위중증환인유교호적료효.
Objective To investigate the application of blood purification for critical disease with non-renal indications in PICU. Methods We retrospectively analyzed the clinical data of 10 critical disease cases with non-renal indications in PICU admitted from Jan to Dec 2009. Five cases were with acute liver failure,2 with autoimmune disease (1 with Guillaln-Barre syndrome, 1 with systemic juvenile rheumatoid arthritis with macrophage activation syndrome) ,2 with severe sepsis,one with metabolic diseases. Results Four cases were treated with plasma exchange combined with continuous veno-venous hemmofiltration. Three cases were treated with continuous veno-venous hemmofiltration. Three cases were treated with plasma exchange.Conclusion CBP is an effective and safe method in the treatment of critical diseases with non-renal indications in PICU.