CAJ | 학술논문

目的通过对比基于CT的肺容量测算结果与常规肺功能检查结果之间的相关性,评估CT测量肺容量法的可靠性和临床意义.方法选取北京儿童医院骨科入院治疗的共计40例早发性胸段脊柱侧弯患儿,行肺功能检查和CT检查.应用手绘-分层测量求和法测量患儿肺容量并计算其与预计值之间比例.将结果与患儿常规肺功能结果进行对比,利用文献报道的CT测量的肺容量正常值作为标准数据,比较基于CT的肺容量实测值/预计值与肺功能相应结果的相关性;比较Cobb's角与凹侧、凸侧肺容量比及肺功能结果之间关系.结果基于CT肺容量结果最大肺活量(VCmax)、用力肺活量(FVC)、肺总量(TLC)平均值低于肺功能检查结果.但与常规肺功能结果的相关性具有统计学意义:VCmax(P<0.001)、FVC(P<0.001)、TLC(P<0.001);基于CT的肺容量实测值/预计值比例与肺功能结果相关性均有统计学意义:Vcmax%(P<0.001)、FVC%(P<0.001)、TLC%(P<0.001);Cobb's角与凹侧、凸侧肺容量比及肺功能结果均无明显关联.结论基于CT的肺容量测算法测量的肺容积结果与常规肺功能结果高度相关,是临床评估患儿肺脏容积的一种有效方法 .
목적 통과대비기우CT적폐용량측산결과여상규폐공능검사결과지간적상관성,평고CT측량폐용량법적가고성화림상의의.방법 선취북경인동의원골과입원치료적공계40례조발성흉단척주측만환인,행폐공능검사화CT검사.응용수회-분층측량구화법측량환인폐용량병계산기여예계치지간비례.장결과여환인상규폐공능결과진행대비,이용문헌보도적CT측량적폐용량정상치작위표준수거,비교기우CT적폐용량실측치/예계치여폐공능상응결과적상관성;비교Cobb's각여요측、철측폐용량비급폐공능결과지간관계.결과기우CT폐용량결과최대폐활량(VCmax)、용력폐활량(FVC)、폐총량(TLC)평균치저우폐공능검사결과.단여상규폐공능결과적상관성구유통계학의의:VCmax(P<0.001)、FVC(P<0.001)、TLC(P<0.001);기우CT적폐용량실측치/예계치비례여폐공능결과상관성균유통계학의의:Vcmax%(P<0.001)、FVC%(P<0.001)、TLC%(P<0.001);Cobb's각여요측、철측폐용량비급폐공능결과균무명현관련.결론 기우CT적폐용량측산법측량적폐용적결과여상규폐공능결과고도상관,시림상평고환인폐장용적적일충유효방법 .
Objective To evaluate the accuracy of the application of CT-based pulmonary volu-metric evaluation to diagnose early onset seoliosis. Methods Forty patients with early-onset thoracic scoliosis were enrolled in this study. All patients had CT scan and pulmonary function test (PFT). Handdraw-layers summation method was carried out to calculate patients'lung volume on CT scan. The reference CT-based lung volume was defined as the corranonly'accepted data reported in litera-tures. The ratio of CT-based patients'lung volume to the reference CT-based lung volume was calcu-lated. The correlation between the calculated ratio and corresponding PFT results was analyzed statis-tically. The correlations between Cobb's angle and concave/convex lung's volume and PFT results were also analyzed. Results Compared to the lung volume of VCmax、FVC、TLC evaluated by PFT,the CT-based lung volume was underestimated. However,the correlation of the lung volume estimated by 2 methods was significant. No significant correlation was found between Cobb's angle or concave/con-vex lung's volume and PFT results. Conclusions Conclusions CT-based Pulmonary Volumetric Evalua-tion is a useful way to evaluate the lung's volume and diagnose early onset scoliosis.