中华口腔医学杂志
中華口腔醫學雜誌
중화구강의학잡지
Chinese Journal of Stomatology
2009年
4期
240-242
,共3页
牛丽娜%陈吉华%方明%杨聚才%焦凯
牛麗娜%陳吉華%方明%楊聚纔%焦凱
우려나%진길화%방명%양취재%초개
复合树脂类%四针状氧化锌晶须%无机载银抗菌荆%抗菌性
複閤樹脂類%四針狀氧化鋅晶鬚%無機載銀抗菌荊%抗菌性
복합수지류%사침상양화자정수%무궤재은항균형%항균성
Composite resins%Tetrapod-like zinc oxide whiskers%Silver-based inorganic antibacterial agent%Antibacterial activity
目的 研究四针状氧化锌晶须(tetrapod-like zinc oxide whiskers,T-ZnOw)抗菌剂对复合树脂抗菌性能的影响,为减少树脂修复后继发龋提供新方法.方法 液体稀释法测试T-ZnOw和无机载银抗菌剂对变形链球菌的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimal bactericidal concentration,MBC).复合树脂粉剂中分别加入质量分数为3%、5%、10%的T-ZnOw和质量分数分别为l%、3%、5%的无机载银抗菌剂,直接接触法测定抗菌率,比较树脂样本加速老化处理3个月后的抗菌率.结果 T-ZnOw和无机载银抗菌剂的MIC分别为0.15625、0.15625 g/L,MBC分别为0.3125、0.15625 g/L.T-ZnOw质量分数为3%、5%、10%时,树脂对变形链球菌的抗菌率分别为(84.85±5.16)%、(94.22±3.73)%、(99.43±0.48)%.无机载银抗菌剂质量分数为1%、3%、5%时,复合树脂的抗菌率分别为(71.01±7.67)%、(90.76±5.91)%、(97.19±4.10)%.老化后添加5%T-ZnOw和5%无机载银抗菌剂的树脂抗菌率分别为(89.89±5.55)%和(78.79±7.81)%.结论 添加T-ZnOw可赋予复合树脂抗菌性能,其质量分数达5%时即可取得较好的抗菌效果,且抗菌长效性优于无机载银抗菌剂.
目的 研究四針狀氧化鋅晶鬚(tetrapod-like zinc oxide whiskers,T-ZnOw)抗菌劑對複閤樹脂抗菌性能的影響,為減少樹脂脩複後繼髮齲提供新方法.方法 液體稀釋法測試T-ZnOw和無機載銀抗菌劑對變形鏈毬菌的最小抑菌濃度(minimal inhibitory concentration,MIC)及最小殺菌濃度(minimal bactericidal concentration,MBC).複閤樹脂粉劑中分彆加入質量分數為3%、5%、10%的T-ZnOw和質量分數分彆為l%、3%、5%的無機載銀抗菌劑,直接接觸法測定抗菌率,比較樹脂樣本加速老化處理3箇月後的抗菌率.結果 T-ZnOw和無機載銀抗菌劑的MIC分彆為0.15625、0.15625 g/L,MBC分彆為0.3125、0.15625 g/L.T-ZnOw質量分數為3%、5%、10%時,樹脂對變形鏈毬菌的抗菌率分彆為(84.85±5.16)%、(94.22±3.73)%、(99.43±0.48)%.無機載銀抗菌劑質量分數為1%、3%、5%時,複閤樹脂的抗菌率分彆為(71.01±7.67)%、(90.76±5.91)%、(97.19±4.10)%.老化後添加5%T-ZnOw和5%無機載銀抗菌劑的樹脂抗菌率分彆為(89.89±5.55)%和(78.79±7.81)%.結論 添加T-ZnOw可賦予複閤樹脂抗菌性能,其質量分數達5%時即可取得較好的抗菌效果,且抗菌長效性優于無機載銀抗菌劑.
목적 연구사침상양화자정수(tetrapod-like zinc oxide whiskers,T-ZnOw)항균제대복합수지항균성능적영향,위감소수지수복후계발우제공신방법.방법 액체희석법측시T-ZnOw화무궤재은항균제대변형련구균적최소억균농도(minimal inhibitory concentration,MIC)급최소살균농도(minimal bactericidal concentration,MBC).복합수지분제중분별가입질량분수위3%、5%、10%적T-ZnOw화질량분수분별위l%、3%、5%적무궤재은항균제,직접접촉법측정항균솔,비교수지양본가속노화처리3개월후적항균솔.결과 T-ZnOw화무궤재은항균제적MIC분별위0.15625、0.15625 g/L,MBC분별위0.3125、0.15625 g/L.T-ZnOw질량분수위3%、5%、10%시,수지대변형련구균적항균솔분별위(84.85±5.16)%、(94.22±3.73)%、(99.43±0.48)%.무궤재은항균제질량분수위1%、3%、5%시,복합수지적항균솔분별위(71.01±7.67)%、(90.76±5.91)%、(97.19±4.10)%.노화후첨가5%T-ZnOw화5%무궤재은항균제적수지항균솔분별위(89.89±5.55)%화(78.79±7.81)%.결론 첨가T-ZnOw가부여복합수지항균성능,기질량분수체5%시즉가취득교호적항균효과,차항균장효성우우무궤재은항균제.
Objective To evaluate effects of incorporating tetrapod-like zinc oxide whisker (T-ZnOw) antibacterial agent on the antibacterial activity of composite resin, compared with that of the silver-based inorganic antibacterial agent. Methods The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of the two different antibacterial agents against Streptococcus mutans were investigated using the broth dilution test Then the antibacterial activities of the self-cured composite resin specimens with different incorporating concentrations of the two antibacterial agents were evaluated using direct contact test And the antibacterial activities of the resin specimens were examined again after 3 months of accelerating aging. Results The MIC (MBC) of the T-ZnOw antibacterial agent and silver-based inorganic antibacterial agent were 0.15625(0.3125) g/L and 0. 15625(0.15625) g/L When the concentrations of T-ZnOw added to composite resin were 3%, 5% , and 10% (w/w), the antibacterialratios of the resin specimens were (84.85±5.16)%, (94.22 ± 3.73)%, and (99.43±0.48)%respectively. When the concentrations of the silver-based antibacterial agent added to composite resin were 1%, 3%, and 5%, the antibacterial ratios were (71.01±7.67)%, (90.76±5.91)%, and (97. 19 ±4.10)% respectively. The antibacterial ratios of the resin specimens containing 5% of both antibacterial agents were (89.89 ± 5.55) % and (78.79 ± 7.81) % respectively after 3 months of accelerating aging.Conclusions Incorporation of the T-ZnOw antibacterial agent in composite resin can improve the antibacterial performance of the resin, and the resin exhibits better antibacterial performance than that incorporating silver-based inorganic antibacterial agent after 3 months of aging.
