CAJ | 학술논문

目的探讨亚急性联合变性(SCD)的临床及辅助检查特点,以期早期诊断.方法对20例SCD的临床资料进行回顾性分析.结果 20例SCD病人中脊髓后侧索均变性18例(90%),周围神经变性17例(85%),大脑白质变性2例(10%),贫血8例(40%).头颅CT检查白质低密度2例(2/8),脊髓MRI异常8例(8/8).血清VitB12浓度降低8例(8/15,53.33%).结论 SCD主要损伤脊髓后侧索及周围神经,血清VitB12浓度测定及脊髓MRI有助于早期诊断及鉴别诊断.
목적 탐토아급성연합변성(SCD)적림상급보조검사특점,이기조기진단.방법 대20례SCD적림상자료진행회고성분석.결과 20례SCD병인중척수후측색균변성18례(90%),주위신경변성17례(85%),대뇌백질변성2례(10%),빈혈8례(40%).두로CT검사백질저밀도2례(2/8),척수MRI이상8례(8/8).혈청VitB12농도강저8례(8/15,53.33%).결론 SCD주요손상척수후측색급주위신경,혈청VitB12농도측정급척수MRI유조우조기진단급감별진단.
Objective To investigate the clinical and auxiliary examination characteristics of patients with subacute combined degeneration(SCD)to earlier diagnosis.Methods The clinical data of 20 cases of SCD were analyzed retrospectively.Results Twenty cases of SCD patients had 18 cases (90%)degeneration in the posterior and lateral columns of spinal cord,17 cases(85%)in peripheral nerve,2 cases(10%)in white matter,8 cases(40%)in anemia.Two cases(2/8)had Leukoaraiosis of CT scan,8 cases(8/8)had spinal cord of MRI abnormality.Eight cases(8/15,53.33%)had serum Vita B12 concentrations decreased.Conclusions SCD major injury of the posterior and lateral columns of spinal cord and the peripheral nerve,VitB12 concentration of the serum and spinal cord MRI can help ear lier diagnosis and differential diagnosis.