CAJ | 학술논문

报告l例寻常性银屑病并发成人型线状IgA大疱性皮病.患者男,36岁.因全身红色斑疹伴白色鳞屑反复发生20年.躯干、双上肢出现环状排列的水疱10d伴瘙痒就诊.皮损组织病理检查:表皮下水疱,疱内、真皮浅层和真皮乳头见中性粒细胞、嗜酸性粒细胞浸润;皮损周围皮肤直接免疫荧光显示基膜带Iga、IgG呈带状沉积;取患者血清行BP180NC16A(大疱性类天疱疮18 000抗原的近膜片段)-ELISA检查显示阴性;以盐裂正常人皮肤为底物,取患者血清行间接免疫荧光检查显示IgA、IgG呈带状沉积在真皮侧.诊断为寻常性银屑病并发成人型线状TgA大疱性皮病.
보고l례심상성은설병병발성인형선상IgA대포성피병.환자남,36세.인전신홍색반진반백색린설반복발생20년.구간、쌍상지출현배상배렬적수포10d반소양취진.피손조직병리검사:표피하수포,포내、진피천층화진피유두견중성립세포、기산성립세포침윤;피손주위피부직접면역형광현시기막대Iga、IgG정대상침적;취환자혈청행BP180NC16A(대포성류천포창18 000항원적근막편단)-ELISA검사현시음성;이염렬정상인피부위저물,취환자혈청행간접면역형광검사현시IgA、IgG정대상침적재진피측.진단위심상성은설병병발성인형선상TgA대포성피병.
To report a case of psoriasis vulgaris combined with adult linear Igt bullous disease.A 36-year-old male who presented with a 20 years history of stable chronic psoriasis vulgaris developed linear IgA bullous disease in 10 days,which displayed blister around erythematous plaques.Histology of lesional skin showed subepidermal bulla containing a mixture of inflammatory cells with predominating neutrophils.Direct immunofluorescence of perilesional skin showed linear deposition of IgA and IgG along the basement membrane zone.ELISA of serum with BP280NC16A showed negative.Indirect immunoflores-cence of serum with salt-split normal human skin showed the presence of IgA and IgG auto-antibodies by the side of derma.The cage was rare psoriasis vulgaris complicated by an adult linear IgA bullous disease.