中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2011年
3期
328-330
,共3页
体外膜氧合作用/方法%体外循环%复温
體外膜氧閤作用/方法%體外循環%複溫
체외막양합작용/방법%체외순배%복온
Extracorporeal membrane oxygenation/MT%Extracorporeal circulation%Rewarming
目的 比较DDMO-100S膜肺与Terumo SX-10膜肺用于小儿体外循环的气体交换与复温的性能.方法 选择3～12岁先天性心脏病患儿39例,拟在体外循环下行房室缺修补术,随机分为DD组(n=21)和SX组(n=18),DD组用DDMO-100S膜肺(西安岱岱,中国),SX组用Terumo SX-10膜肺(Terumo,日本).采用中低温中高流量CPB,冠脉灌注冷晶体停跳液.于转机后15 min和停机前5 min抽取动脉血行血气分析,并计算氧合指数(OI)(OI=PaO2/FiO2).监测鼻咽温度并记录复温时间.结果 实际总预充量DD组＞SX组[(742.5±107.3)ml vs(531.3±84.3ml),P＜0.05];两组转机后15 min停机前5 min的PO2、PCO2和氧合指数(OI)差异无统计学意义(P＞0.05);两组复温时间差异无统计学意义[(31.5±10.2)min vs(30.6±8.2)min,P＞0.05].结论 在观察条件下,DDMO-100S膜肺和Terumo SX-10膜肺的气体交换与复温的性能相当,实际总预充量稍大.
目的 比較DDMO-100S膜肺與Terumo SX-10膜肺用于小兒體外循環的氣體交換與複溫的性能.方法 選擇3～12歲先天性心髒病患兒39例,擬在體外循環下行房室缺脩補術,隨機分為DD組(n=21)和SX組(n=18),DD組用DDMO-100S膜肺(西安岱岱,中國),SX組用Terumo SX-10膜肺(Terumo,日本).採用中低溫中高流量CPB,冠脈灌註冷晶體停跳液.于轉機後15 min和停機前5 min抽取動脈血行血氣分析,併計算氧閤指數(OI)(OI=PaO2/FiO2).鑑測鼻嚥溫度併記錄複溫時間.結果 實際總預充量DD組＞SX組[(742.5±107.3)ml vs(531.3±84.3ml),P＜0.05];兩組轉機後15 min停機前5 min的PO2、PCO2和氧閤指數(OI)差異無統計學意義(P＞0.05);兩組複溫時間差異無統計學意義[(31.5±10.2)min vs(30.6±8.2)min,P＞0.05].結論 在觀察條件下,DDMO-100S膜肺和Terumo SX-10膜肺的氣體交換與複溫的性能相噹,實際總預充量稍大.
목적 비교DDMO-100S막폐여Terumo SX-10막폐용우소인체외순배적기체교환여복온적성능.방법 선택3～12세선천성심장병환인39례,의재체외순배하행방실결수보술,수궤분위DD조(n=21)화SX조(n=18),DD조용DDMO-100S막폐(서안대대,중국),SX조용Terumo SX-10막폐(Terumo,일본).채용중저온중고류량CPB,관맥관주랭정체정도액.우전궤후15 min화정궤전5 min추취동맥혈행혈기분석,병계산양합지수(OI)(OI=PaO2/FiO2).감측비인온도병기록복온시간.결과 실제총예충량DD조＞SX조[(742.5±107.3)ml vs(531.3±84.3ml),P＜0.05];량조전궤후15 min정궤전5 min적PO2、PCO2화양합지수(OI)차이무통계학의의(P＞0.05);량조복온시간차이무통계학의의[(31.5±10.2)min vs(30.6±8.2)min,P＞0.05].결론 재관찰조건하,DDMO-100S막폐화Terumo SX-10막폐적기체교환여복온적성능상당,실제총예충량초대.
Objective To compare the gas and heat exchange performance of membrane oxygenator DDMO-100S and membrane oxygenator Terumo SX-10 in cardiopulmonary bypass(CPB)in children.Methods 39 children aged 3-12 yrs who suffered from congenital heart disease were selected,and the repair of ventricle septal defect or/and atrial septal defect was performed under cardiopulmonary bypass.The 39 children were randomly divided into Group DD(n =21)and Group SX(n = 18).Membrane oxygenator DDMO-100S(Made by Xi'an Daidai,China)was used in Group DD and Membrane oxygenator Terumo SX-10(Made by Terumo,Japan)in Group SX,respectively.The hypothermic cardiopulmonary bypass with high perfusion flow and the cool crystalloid cardioplegia were applied in all children.The artery blood samples were taken for measuring PO2 and PCO2 and the oxygenating index(OI)was calculated by the formulae(OI = PaO2/FiO2).The temperature at nasal pharynx was monitored and the rewarming time was recorded.Results The total priming volume in Group DD was bigger than in Group SX [(742.5 ± 107.3)ml vs(531.3 ± 84.3)ml,P ＜ 0.05].The PO2,OI and PCO2 at 15 min after CPB or at 5 min before cease of CPB had no differences in both group(P ＞0.05).The rewarming time had no difference in both group [(31.5 ± 10.2)min vs(30.61 ± 8.2)min,P ＞0.05].Conclusions Under our observation condition,the gas and heat exchange performance of membrane oxygenator DDMO-100S were the same as membrane oxygenator Terumo SX-10,when it was used in cardiopulmonary bypass in children,but it had a little bit more priming volume.
