CAJ | 학술논문

目的评价新型无框架立体定向系统VarioGuide在颅内病变穿刺活检中的应用价值.方法 2011年11月至2012年4月解放军总医院神经外科15例颅内病变患者,接受VarioGuide联合多模态神经导航辅助下的立体定向穿刺活检.术中磁共振(iMRI)用于验证活检的准确性.记录不良事件、手术时间、手术结果及术后并发症.结果所有病例均成功实施了VarioGuide联合多模态神经导航辅助下的立体定向穿刺活检,无VarioGuide相关不良事件.手术平均耗时(65±8)min,iMRI证实全部穿刺位点与预设靶点完全吻合.术后全部标本均获得病理诊断,无死亡或其他术后并发症.结论 VarioGuide联合多模态神经导航是一种准确、安全、高效的技术手段,能够在不增加术后神经功能障碍的前提下,提高活检手术的阳性诊断率.
목적 평개신형무광가입체정향계통VarioGuide재로내병변천자활검중적응용개치.방법 2011년11월지2012년4월해방군총의원신경외과15례로내병변환자,접수VarioGuide연합다모태신경도항보조하적입체정향천자활검.술중자공진(iMRI)용우험증활검적준학성.기록불량사건、수술시간、수술결과급술후병발증.결과 소유병례균성공실시료VarioGuide연합다모태신경도항보조하적입체정향천자활검,무VarioGuide상관불량사건.수술평균모시(65±8)min,iMRI증실전부천자위점여예설파점완전문합.술후전부표본균획득병리진단,무사망혹기타술후병발증.결론 VarioGuide연합다모태신경도항시일충준학、안전、고효적기술수단,능구재불증가술후신경공능장애적전제하,제고활검수술적양성진단솔.
Objective To evaluate the clinical value of VarioGuide in stereotactic brain biopsy.Methods Fifteen patients with brain lesions underwent frameless stereotactic brain biopsy guided by VarioGuide and multimodal neuronavigation.Intraoperative magnetic resonance imaging (iMRI) was used to confirm the accuracy of biopsy. And the VarioGuide-related adverse events,operative duration,surgical outcomes and postoperative complications were recorded respectively.Results In all patients,VarioGuide and multimodal neuronavigation were successfully integrated into the biopsy procedure. No VarioGuiderelated adverse events were reported.The mean operative duration was (65 ± 8) min.The biopsy accuracy was confirmed by iMRI in all cases.And the postoperative histological diagnostic rate was 100％.No mortality and morbidity occurred postoperatively.Conclusion The combined approach of VarioGuide and multimodal neuronavigation is accurate,safe and efficient.It may improve the histological diagnostic rate without postoperative neurological deficits in stereotactic brain biopsy.