中华移植杂志（电子版）
中華移植雜誌（電子版）
중화이식잡지（전자판）
Chinese Journal of Transplantation(Electronic Version)
2009年
2期
119-122
,共4页
许龙根%徐惠明%朱晓峰%吴颖
許龍根%徐惠明%硃曉峰%吳穎
허룡근%서혜명%주효봉%오영
慢性肾功能不全尿毒症期%肾移植%睾丸体积%生育能力
慢性腎功能不全尿毒癥期%腎移植%睪汍體積%生育能力
만성신공능불전뇨독증기%신이식%고환체적%생육능력
Uremia%Kidney transplantation%Testicular volume%Male reproductive ability
目的 探讨肾移植对男性慢性肾功能不全尿毒症期患者睾丸体积及生育力指数的影响.方法 解放军第117医院肾移植中心30例慢性肾功能不全尿毒症期患者于肾移植术前以及术后1个月、3个月和1年应用彩超进行睾丸体积监测,并与20名正常男性的睾丸体积比较.另检测40例尿毒症期和40例肾移植受者的精液,并根据公式[精子密度(×106/mL)×精子活动力×精子正常形态率]计算出生育力指数.结果 慢性肾功能不全尿毒症期患者的睾丸体积术前左侧为(6.82±1.49)mL, 右侧为(7.46±1.89)mL;肾移植术后1个月、3个月和1年左侧分别为(8.25±1.67)mL、(9.31±1.56) mL和(9.80±1.51)mL,右侧分别为(9.18±1.76) mL、(10.41±1.43) mL和(11.09±1.45)mL,肾移植受者术后1个月、3个月和1年的睾丸体积均大于尿毒症期患者,差异有显著性意义(均P<0.01).正常对照组生育力指数为13.03(14.26),肾移植受者的生育力指数为7.19(10.18), 而尿毒症期患者的生育力指数仅为0.23(0.76).尿毒症期患者的生育力指数比肾移植受者和正常对照组均小,差异有显著性意义(均P<0.01). 结论 慢性肾功能不全尿毒症期患者睾丸体积缩小,生育力指数下降, 而成功的肾移植可以明显改善尿毒症期患者的睾丸体积及生育力指数.
目的 探討腎移植對男性慢性腎功能不全尿毒癥期患者睪汍體積及生育力指數的影響.方法 解放軍第117醫院腎移植中心30例慢性腎功能不全尿毒癥期患者于腎移植術前以及術後1箇月、3箇月和1年應用綵超進行睪汍體積鑑測,併與20名正常男性的睪汍體積比較.另檢測40例尿毒癥期和40例腎移植受者的精液,併根據公式[精子密度(×106/mL)×精子活動力×精子正常形態率]計算齣生育力指數.結果 慢性腎功能不全尿毒癥期患者的睪汍體積術前左側為(6.82±1.49)mL, 右側為(7.46±1.89)mL;腎移植術後1箇月、3箇月和1年左側分彆為(8.25±1.67)mL、(9.31±1.56) mL和(9.80±1.51)mL,右側分彆為(9.18±1.76) mL、(10.41±1.43) mL和(11.09±1.45)mL,腎移植受者術後1箇月、3箇月和1年的睪汍體積均大于尿毒癥期患者,差異有顯著性意義(均P<0.01).正常對照組生育力指數為13.03(14.26),腎移植受者的生育力指數為7.19(10.18), 而尿毒癥期患者的生育力指數僅為0.23(0.76).尿毒癥期患者的生育力指數比腎移植受者和正常對照組均小,差異有顯著性意義(均P<0.01). 結論 慢性腎功能不全尿毒癥期患者睪汍體積縮小,生育力指數下降, 而成功的腎移植可以明顯改善尿毒癥期患者的睪汍體積及生育力指數.
목적 탐토신이식대남성만성신공능불전뇨독증기환자고환체적급생육력지수적영향.방법 해방군제117의원신이식중심30례만성신공능불전뇨독증기환자우신이식술전이급술후1개월、3개월화1년응용채초진행고환체적감측,병여20명정상남성적고환체적비교.령검측40례뇨독증기화40례신이식수자적정액,병근거공식[정자밀도(×106/mL)×정자활동력×정자정상형태솔]계산출생육력지수.결과 만성신공능불전뇨독증기환자적고환체적술전좌측위(6.82±1.49)mL, 우측위(7.46±1.89)mL;신이식술후1개월、3개월화1년좌측분별위(8.25±1.67)mL、(9.31±1.56) mL화(9.80±1.51)mL,우측분별위(9.18±1.76) mL、(10.41±1.43) mL화(11.09±1.45)mL,신이식수자술후1개월、3개월화1년적고환체적균대우뇨독증기환자,차이유현저성의의(균P<0.01).정상대조조생육력지수위13.03(14.26),신이식수자적생육력지수위7.19(10.18), 이뇨독증기환자적생육력지수부위0.23(0.76).뇨독증기환자적생육력지수비신이식수자화정상대조조균소,차이유현저성의의(균P<0.01). 결론 만성신공능불전뇨독증기환자고환체적축소,생육력지수하강, 이성공적신이식가이명현개선뇨독증기환자적고환체적급생육력지수.
Objective To investigate the effect of kidney transplantation on male fertility index and testicular volume in patients with uremia.Methods Testicular volume in 30 patients who underwent kidney transplantation for uremia was monitored by color ultrasound before and in 1,3 and 12 months after kidney transplantation. Semen samples from 40 uremia patients and 40 kidney transplant recipients were tested for fertility index (FI) calculation. FI=sperm concentration(×106/mL)×sperm viability ×sperm normal morphology rate. Another 20 and 40 normal male subjects served as control were measured testicular volume and FI, respectively.Results Testicular volume of uremia patients before surgery was(6.82±1.49)mL on the left side and (7.46±1.89) mL on the right side. In 1, 3, and 12 months after kidney transplantation, testicular volume on the left side increased to (8.25±1.67),(9.31±1.56),and (9.80±1.51) mL and that on the right side rose to (9.18±1.76),(10.41±1.43),(11.09±1.45) mL, respectively. FI was 13.03(14.26)in normal subjects, 7.19(10.18)in kidney transplant recipients, and 0.23(0.76) in uremia patients. Testicular volume and FI between uremia patients and after kidney transplant groups had statistical differences (P<0.01).Conclusion Male testicular volume and fertility index is reduced by uremia, and this reduction can be improved with successful kidney transplantation.
