中国循证医学杂志
中國循證醫學雜誌
중국순증의학잡지
CHINESE JOURNAL OF EVIDENCE-BASED MEDICINE
2010年
1期
30-32
,共3页
急性特发性面神经麻痹%三七通舒胶囊%临床对照试验%House-Brackmann%面神经电图
急性特髮性麵神經痳痺%三七通舒膠囊%臨床對照試驗%House-Brackmann%麵神經電圖
급성특발성면신경마비%삼칠통서효낭%림상대조시험%House-Brackmann%면신경전도
Acute idiopathic facial paralysis%Sanqi Tongshu capsule%Clinical controlled trial%House-Brackmann%Facial electroneurogram
目的 探讨三七通舒对急性特发性面神经麻痹的疗效.方法 将86例特发性面神经麻痹急性期(发病7天内)患者分为两组,对照组42例采用激素、B族维生素、抗病毒治疗以及针灸理疗等基础治疗,三七通舒组44例采用基础治疗+三七通舒治疗,疗程28天.采用House-Brackmann面神经功能分级评定及临床疗效指标判定.治疗前后行面神经电图(ENoG)检查.结果 治疗前两组H-B面神经功能分级、患侧EnoG的潜伏期及振幅均具有可比性.治疗28天后,两组H-B评分比较差异有统计学意义(治疗组2.33±1.21 vs对照组3.08±1.35,P<0.05);面神经电图显示治疗组患侧潜伏期(2.46±0.34)及振幅(189±67)均较对照组潜伏期(3.37±0.49)及振幅(131±52)有改善,两组差异有统计学意义(P<0.05);临床疗效指标比较显示两组总有效率分别为:治疗组95.45%,对照组80.95%,治疗组明显优于对照组,两组差异有统计学意义(P<0.05).结论 三七通舒胶囊联合激素、B族维生素、抗病毒、针灸及理疗等综合治疗对急性特发性面神经麻痹有效.
目的 探討三七通舒對急性特髮性麵神經痳痺的療效.方法 將86例特髮性麵神經痳痺急性期(髮病7天內)患者分為兩組,對照組42例採用激素、B族維生素、抗病毒治療以及針灸理療等基礎治療,三七通舒組44例採用基礎治療+三七通舒治療,療程28天.採用House-Brackmann麵神經功能分級評定及臨床療效指標判定.治療前後行麵神經電圖(ENoG)檢查.結果 治療前兩組H-B麵神經功能分級、患側EnoG的潛伏期及振幅均具有可比性.治療28天後,兩組H-B評分比較差異有統計學意義(治療組2.33±1.21 vs對照組3.08±1.35,P<0.05);麵神經電圖顯示治療組患側潛伏期(2.46±0.34)及振幅(189±67)均較對照組潛伏期(3.37±0.49)及振幅(131±52)有改善,兩組差異有統計學意義(P<0.05);臨床療效指標比較顯示兩組總有效率分彆為:治療組95.45%,對照組80.95%,治療組明顯優于對照組,兩組差異有統計學意義(P<0.05).結論 三七通舒膠囊聯閤激素、B族維生素、抗病毒、針灸及理療等綜閤治療對急性特髮性麵神經痳痺有效.
목적 탐토삼칠통서대급성특발성면신경마비적료효.방법 장86례특발성면신경마비급성기(발병7천내)환자분위량조,대조조42례채용격소、B족유생소、항병독치료이급침구리료등기출치료,삼칠통서조44례채용기출치료+삼칠통서치료,료정28천.채용House-Brackmann면신경공능분급평정급림상료효지표판정.치료전후행면신경전도(ENoG)검사.결과 치료전량조H-B면신경공능분급、환측EnoG적잠복기급진폭균구유가비성.치료28천후,량조H-B평분비교차이유통계학의의(치료조2.33±1.21 vs대조조3.08±1.35,P<0.05);면신경전도현시치료조환측잠복기(2.46±0.34)급진폭(189±67)균교대조조잠복기(3.37±0.49)급진폭(131±52)유개선,량조차이유통계학의의(P<0.05);림상료효지표비교현시량조총유효솔분별위:치료조95.45%,대조조80.95%,치료조명현우우대조조,량조차이유통계학의의(P<0.05).결론 삼칠통서효낭연합격소、B족유생소、항병독、침구급리료등종합치료대급성특발성면신경마비유효.
Objective To evaluate the effect of PNS on Idiopathic facial palsy. Methods A total of 86 cases of acute idiopathic facial paralysis were randomly divided into the treatment group (PNS group, 44 cases), and the control group (42 cases). The basis of the two groups included hormone therapy, B vitamins, anti-viral treatment, as well as acupuncture and physical therapy, both in the incidence of 7 days to give the treatment. House-Brackmann facial nerve function classification and evaluation were used to determine clinical efficacy; ENoG line was tested before and after treatment. Results Before H-B classification of facial nerve function, EnoG side of the latency and amplitude in the two groups were comparable. At 28 days after treatment, H-B scores for the treatment group and the control group were (2.33 ± 1.21) and (3.08 ± 1.35), respectively, and the two groups had significant differences (P<0.05); ENoG incubation period (2.46 ± 0.34) and amplitude (189 ± 67) of the treatment group were more than those of the control group; the incubation period (3.37 ± 0.49) and amplitude (131 ± 52) improved, and there were significant differences between the two groups (P<0.05). Comparison of efficacy of the two groups showed the total effective rate: 95.45% in the treatment group, 80.95% in the control group, and the efficacy of the treatment group was better than that of the control group (P<0.05). Conclusion Sanqi tongshu, B vitamins, anti-virus, such as the acupuncture and physical therapy for the treatment of acute idiopathic facial paralysis have significant effect.
