胃动素受体基因SNP位点的筛选及其与糖尿病胃轻瘫的关系
위동소수체기인SNP위점적사선급기여당뇨병위경탄적관계
Primary screening of cSNP sites of human motilin receptor gene
  • 万方数据
    中国糖尿病杂志 중국당뇨병잡지
    CHINESE JOURNAL OF DIABETES
    2006年 2期 101-102 ,共2页

    王志刚%郑起%贾伟平%张奎星

    왕지강%정기%가위평%장규성

    受体,促胃动素%单核甘酸多态性%胃肌轻瘫 受體,促胃動素%單覈甘痠多態性%胃肌輕癱
    수체,촉위동소%단핵감산다태성%위기경탄
    Diabetic gastroparesis
    G蛋白偶联受体-胃动素受体基因(GPR38)第一外显子177位碱基存在A/C变异;第一外显子799位存在C/T变异,均未改变氨基酸编码.提示糖尿病胃轻瘫的易感性与GPR38的单核甘酸多态性可能没有关系.本研究补充了GPR38 SNPs的数据库信息.
    G단백우련수체-위동소수체기인(GPR38)제일외현자177위감기존재A/C변이;제일외현자799위존재C/T변이,균미개변안기산편마.제시당뇨병위경탄적역감성여GPR38적단핵감산다태성가능몰유관계.본연구보충료GPR38 SNPs적수거고신식.
    The PCR-amplified products of 2 exons of GPR 38 (motilin receptor) gene were directly sequenced in 40 cases with diabetic gastroparesis (DG) and 40 normal subjects (NS). There were 2 SNP sites (117 A/C and 799 C/T) in exon 1, which did not change the codons and there were no differences in the 2 SNP sites between DG and NS.
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