中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2010年
11期
1187-1189
,共3页
诺和龙%2型糖尿病%动脉粥样硬化
諾和龍%2型糖尿病%動脈粥樣硬化
낙화룡%2형당뇨병%동맥죽양경화
Novonorm%Type 2 diabetes%Atherosclerosis
目的 观察诺和龙治疗2型糖尿病合并动脉粥样硬化患者的临床疗效.方法 将65例2型糖尿病合并动脉粥样硬化患者随机分为诺和龙组(36例)和优哒灵组(29例),诺和龙组患者降糖药均为诺和龙治疗,优哒灵组均为优哒灵治疗,观察疗程12个月,监测治疗前后的血糖含量和颈动脉内膜中层厚度.结果 诺和龙组能有效降低餐后血糖(1.99±1.06)mmol/L,优哒灵降低餐后血糖(0.99±0.54)mmol/L,2组比较差异有统计学意义(P＜0.05).诺和龙组治疗后颈动脉内膜中层厚度比治疗前减少[(1.02±0.08)、(1.11±0.07)mm](P＜0.05),优哒灵组治疗后颈动脉内膜中层厚度与治疗前比较无差异[(1.07±0.06)、(1.10±0.08)mm](P＞0.05).结论 诺和龙是一种安全、有效的降糖药物,适于2型糖尿病合并动脉粥样硬化患者的治疗.
目的 觀察諾和龍治療2型糖尿病閤併動脈粥樣硬化患者的臨床療效.方法 將65例2型糖尿病閤併動脈粥樣硬化患者隨機分為諾和龍組(36例)和優噠靈組(29例),諾和龍組患者降糖藥均為諾和龍治療,優噠靈組均為優噠靈治療,觀察療程12箇月,鑑測治療前後的血糖含量和頸動脈內膜中層厚度.結果 諾和龍組能有效降低餐後血糖(1.99±1.06)mmol/L,優噠靈降低餐後血糖(0.99±0.54)mmol/L,2組比較差異有統計學意義(P＜0.05).諾和龍組治療後頸動脈內膜中層厚度比治療前減少[(1.02±0.08)、(1.11±0.07)mm](P＜0.05),優噠靈組治療後頸動脈內膜中層厚度與治療前比較無差異[(1.07±0.06)、(1.10±0.08)mm](P＞0.05).結論 諾和龍是一種安全、有效的降糖藥物,適于2型糖尿病閤併動脈粥樣硬化患者的治療.
목적 관찰낙화룡치료2형당뇨병합병동맥죽양경화환자적림상료효.방법 장65례2형당뇨병합병동맥죽양경화환자수궤분위낙화룡조(36례)화우달령조(29례),낙화룡조환자강당약균위낙화룡치료,우달령조균위우달령치료,관찰료정12개월,감측치료전후적혈당함량화경동맥내막중층후도.결과 낙화룡조능유효강저찬후혈당(1.99±1.06)mmol/L,우달령강저찬후혈당(0.99±0.54)mmol/L,2조비교차이유통계학의의(P＜0.05).낙화룡조치료후경동맥내막중층후도비치료전감소[(1.02±0.08)、(1.11±0.07)mm](P＜0.05),우달령조치료후경동맥내막중층후도여치료전비교무차이[(1.07±0.06)、(1.10±0.08)mm](P＞0.05).결론 낙화룡시일충안전、유효적강당약물,괄우2형당뇨병합병동맥죽양경화환자적치료.
Objective To assess the clinical effect of Novonorm on treating type 2 diabetic patients with atherosclerosis. Methods Sixty-five patients of type 2 diabetes with atherosclerosis were randomly divided into 2 groups :36 patients took Novonorm,and the other 29 individuals were treated with Glipizide. The blood glucose and CIMT were compared before and after treatment for 12 months. Results The postprandial blood glucose decreased by(1.99 ± 1.06)mmol/L after the treatment of Novonorm,which was significantly higher than that of(0. 99 ±0. 54)mmol/L after the treatment of Glipizide(P ＜ 0. 05). CIMT significantly decreased from (1.11 ± 0. 07)mm before treatment to(1.02 ± 0. 08)mm after treatment in the Novonorm group(P ＜ 0. 05),whereas CIMT were similar between after and before treatment in the Glipizide group(1.07 ± 0. 06)mm vs.(1.10 ± 0. 08)mm(P ＞ 0. 05).Conclusions Novonorm is a kind of effective and safe regent,which can be used to treat type 2 diabetic patients with atherosclerosis.
