CAJ | 학술논문

目的总结同心圆硬化的MRl及弥散加权成像(DWI)特点,并探讨其影像学变化与可能发生机制的相关性.方法总结临床确诊的同心圆硬化患者3例,均行头颅MRI及DWI检查,其中1例患者行氢质子波谱成像(1H-MRS).结果 3例患者均为多发病灶,病灶多位于中央白质区,均可见特征性的"同心圆样"或"洋葱皮样"改变,增强扫描旱环形或半环形强化.DWI见病灶呈高、低交替环形信号,表观扩散系数(ADC)值随同心圆病理的脱髓鞘区与髓鞘保留区相问存在而出现高低相间变化.结论 Balo同心圆硬化MRI和DWI表现具有特征性,可与病理改变对应,为加深该病发生机制认识提供影像学证据.
목적 총결동심원경화적MRl급미산가권성상(DWI)특점,병탐토기영상학변화여가능발생궤제적상관성.방법 총결림상학진적동심원경화환자3례,균행두로MRI급DWI검사,기중1례환자행경질자파보성상(1H-MRS).결과 3례환자균위다발병조,병조다위우중앙백질구,균가견특정성적"동심원양"혹"양총피양"개변,증강소묘한배형혹반배형강화.DWI견병조정고、저교체배형신호,표관확산계수(ADC)치수동심원병리적탈수초구여수초보류구상문존재이출현고저상간변화.결론 Balo동심원경화MRI화DWI표현구유특정성,가여병리개변대응,위가심해병발생궤제인식제공영상학증거.
Objective To sum up the magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) characters in patients with concentric sclerosis, and to investigate the association between imaging and possible pathogenesis.Methods Three patients with clinically diagnosed concentric sclerosis underwent MR] and DWI, one of whom was additionally performed 1H-magnetic resonance spectroscopy imaging (1H-MRS).Results Multiple lesions of laminated demyelination alternating with spared white matter were demonstrated in all 3 patients, and the enhanced lesions appeared to be concentric coils.Rings of alternating hypointense and hyperintense layers were shown on the DWI image, with apparent diffusion coefficient alternating correspondingly to the layers of the histologically demyetinated and undemyelinated areas.Conclusions Balo' s concentric sclerosis has unique characteristics on MRI and DWI, which corresponds to changes in its pathology and provides evidence for a better understanding of its pathophysiologic mechanisms.