黑龙江医药科学
黑龍江醫藥科學
흑룡강의약과학
EHILONGJIANG MEDICINE PHARMACY
2001年
3期
18
,共1页
NIDDM%胰岛素敏感指数
NIDDM%胰島素敏感指數
NIDDM%이도소민감지수
目的：复制非胰岛素依赖型糖尿病(non insulin-dependent diabetesmellitus,NIDDM)模型。方法：给大鼠尾静脉注射小剂量链尿佐菌素，使大鼠糖耐量异常，然后加喂高热量食物。结果：8周后形成NIDDM模型。结论：胰岛素敏感指数可准确反应胰岛素受体数目的多少。
目的：複製非胰島素依賴型糖尿病(non insulin-dependent diabetesmellitus,NIDDM)模型。方法：給大鼠尾靜脈註射小劑量鏈尿佐菌素，使大鼠糖耐量異常，然後加餵高熱量食物。結果：8週後形成NIDDM模型。結論：胰島素敏感指數可準確反應胰島素受體數目的多少。
목적：복제비이도소의뢰형당뇨병(non insulin-dependent diabetesmellitus,NIDDM)모형。방법：급대서미정맥주사소제량련뇨좌균소，사대서당내량이상，연후가위고열량식물。결과：8주후형성NIDDM모형。결론：이도소민감지수가준학반응이도소수체수목적다소。
Objective: To establish establishing a model of non-insulindependent diabetes mellitus (NIDDM). Method: We injected rats with small dose streptozocoi (i.v.). Two weeks after the injection, the rats developed impaired glucose tolerance. Then, they were fed with high energy diet. Results: After eight weeks. NIDDM Model was formed. Insulin sensitive index was decreased compared with controls (P<0.01). Conclusion: Insulin sensitive index may show accurate the number of the insulin receptors.
