CAJ | 학술논문

目的探讨我国城市高血压人群中微量清蛋白尿(MAU)的患病率及危险因素.方法采用分层整群抽样方法,在上海市大场社区的34个居委和3个村按照居住情况和经济状况分别抽取3个居委和1个村的高血压患者为调查对象,对其进行问卷调查,检测尿微量清蛋白、血肌酐、血尿酸、血脂水平.高血压患者肾脏损害的危险因素采用多因素Logistic回归分析.结果在703例高血压患者中,微量清蛋白尿的患病率为16.2%,男性为20.9%,女性为12.9%,男女间差异有统计学意义(P<0.05).不同年龄高血压患者MAU的患病率间差异有统计学意义(P<0.05).入选回归模型的因素:吸烟(OR=1.922)、病程长(OR=1.025)、治疗效果差(OR=1.410)、高尿酸血症(OR=0.328)、血肌酐高(OR=6.582).结论高血压人群中微量清蛋白尿的患病率较高,社区高血压人群肾脏病防治中要积极控制血压、戒烟、降低血尿酸和肌酐的水平.
목적 탐토아국성시고혈압인군중미량청단백뇨(MAU)적환병솔급위험인소.방법 채용분층정군추양방법,재상해시대장사구적34개거위화3개촌안조거주정황화경제상황분별추취3개거위화1개촌적고혈압환자위조사대상,대기진행문권조사,검측뇨미량청단백、혈기항、혈뇨산、혈지수평.고혈압환자신장손해적위험인소채용다인소Logistic회귀분석.결과 재703례고혈압환자중,미량청단백뇨적환병솔위16.2%,남성위20.9%,녀성위12.9%,남녀간차이유통계학의의(P<0.05).불동년령고혈압환자MAU적환병솔간차이유통계학의의(P<0.05).입선회귀모형적인소:흡연(OR=1.922)、병정장(OR=1.025)、치료효과차(OR=1.410)、고뇨산혈증(OR=0.328)、혈기항고(OR=6.582).결론 고혈압인군중미량청단백뇨적환병솔교고,사구고혈압인군신장병방치중요적겁공제혈압、계연、강저혈뇨산화기항적수평.
Objective To investigate the prevalence of microalbuminuria (MAU) and its risk factors in hypertensive population in cities of our country.Methods A questionnaire survey was carried out by stratified cluster sampling method to detect the levels of uric microalbumin,serum creatinine (Cr),serum uric acid (SUA) and blood lipid in hypertensive patients(drawn from 3 of 34 residents' committees,1 of 3 villages according to living and economic conditions ).Risk factors of renal damage were analyzed by multivariate Logistic Regression.Results In 703 hypertensive patients,the prevalence of MAU was 16.2%( 20.9% in males, 12.9% in females ),the difference between males and females and between different age groups with hypertension was significant(P＜0.05).Factors of enrolment regression models were smoking (OR=1.922),longer disease courses(OR=1.025),bad curative effects(OR=1.410),hyperuricemia (OR=0.328)and high Cr(OR=6.582).Conclusion Prevalence of MAU is higher in hypertensive population.Blood pressure,smoking must be controlled and SUA and Cr reduced in prevention and treatment of kidney diseases in community hypertensive population.