中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2010年
2期
151-154
,共4页
陈梦施%杨华林%陈艳芳%谭红专%白丽琼%张艳辉%刘军%李桂平
陳夢施%楊華林%陳豔芳%譚紅專%白麗瓊%張豔輝%劉軍%李桂平
진몽시%양화림%진염방%담홍전%백려경%장염휘%류군%리계평
艾滋病%结核%巢式病例对照研究%影响因素
艾滋病%結覈%巢式病例對照研究%影響因素
애자병%결핵%소식병례대조연구%영향인소
Acquired immunedeficiency syndrome%Tuberculosis%Nested case-control study%Influencing factors
目的 探讨HIV/AIDS人群发生结核病的危险因素.方法 采用1:2匹配的巢式病例对照研究方法分析HIV/AIDS人群发生结核的危险因素.结果 对1018例未患结核的HIV/AIDS人群随访观察1年,累计观察736.75人年,共检查出结核病患者62例,HIV/AIDS人群结核病发病密度为8.42人/100人年(62人/736.75人年).文化程度(OR=0.483)、卡介苗接种史(OR=0.561)、CD_4~+T淋巴细胞数(OR=0.356)、无业(OR=1.976)、单身(OR=2.646)和吸烟(OR=2.215)等因素与HIV/AIDS人群发生结核病有关.结论 文化程度高、有卡介苗接种史和CD_4~+T淋巴细胞数高是HIV/AIDS人群患结核病的保护因素;无业、单身和吸烟是HIV/AIDS人群患结核病的危险因素.
目的 探討HIV/AIDS人群髮生結覈病的危險因素.方法 採用1:2匹配的巢式病例對照研究方法分析HIV/AIDS人群髮生結覈的危險因素.結果 對1018例未患結覈的HIV/AIDS人群隨訪觀察1年,纍計觀察736.75人年,共檢查齣結覈病患者62例,HIV/AIDS人群結覈病髮病密度為8.42人/100人年(62人/736.75人年).文化程度(OR=0.483)、卡介苗接種史(OR=0.561)、CD_4~+T淋巴細胞數(OR=0.356)、無業(OR=1.976)、單身(OR=2.646)和吸煙(OR=2.215)等因素與HIV/AIDS人群髮生結覈病有關.結論 文化程度高、有卡介苗接種史和CD_4~+T淋巴細胞數高是HIV/AIDS人群患結覈病的保護因素;無業、單身和吸煙是HIV/AIDS人群患結覈病的危險因素.
목적 탐토HIV/AIDS인군발생결핵병적위험인소.방법 채용1:2필배적소식병례대조연구방법분석HIV/AIDS인군발생결핵적위험인소.결과 대1018례미환결핵적HIV/AIDS인군수방관찰1년,루계관찰736.75인년,공검사출결핵병환자62례,HIV/AIDS인군결핵병발병밀도위8.42인/100인년(62인/736.75인년).문화정도(OR=0.483)、잡개묘접충사(OR=0.561)、CD_4~+T림파세포수(OR=0.356)、무업(OR=1.976)、단신(OR=2.646)화흡연(OR=2.215)등인소여HIV/AIDS인군발생결핵병유관.결론 문화정도고、유잡개묘접충사화CD_4~+T림파세포수고시HIV/AIDS인군환결핵병적보호인소;무업、단신화흡연시HIV/AIDS인군환결핵병적위험인소.
Objective To determine the risk factors related to tuberculosis infection among people living with HIV/AIDS and to develop strategies for preventing the co-infection.Methods A 1:2matched nested case-control study was carried out to analyze the influencing factors of tuberculosis among people living with HIV/AIDS.Results 1018 people living with HIV/AIDS were followed up for one year with a total number of 736.75 person-years,among them 62 tuberculosis cases were diagnosed.The incidence density of tuberculosis among people living with HIV/AIDS was 8.42 persons per 100 person-years.Factors as education level(OR=0.483),vaccination history of Bacille Calmette Guerin(OR=0.561),CD_4~+ count T-lymphocyte(OR=0.356),unemployment(OR=1.976),living alone(OR=2.646),and smoking(OR=2.215)were significantly related to the prevalence of tuberculosis among people living with HIV/AIDS.Conclusion High education level,with vaccination history of Bacille Calmette Guerin and high level of CD_4~+ T-lymphocyte count were protective factors while being unemployed,living alone,and smoking habit were risk factors related to the prevalence of tuberculosis among people living with HIV/AIDS.
