CAJ | 학술논문

目的探讨青年急性进展型脑梗死患者进展与治疗前后血中D-二聚体(D-D)、高敏 C-反应蛋白(hs-CRP)含量变化与脑梗死发展的关系.方法选择急性脑梗死 A 组(未发生进展)30例、B组(发生进展)20例和正常对照组50例分别测定其hs-CRP、D-D进展及治疗前后含量并加以分析.结果青年急性进展型脑梗死组D-D和 hs-CRP含量明显高于对照组和非进展型脑梗死组(P＜0.01); D-D和 hs-CRP含量经统计学处理呈正相关(r=0.64,P＜0.01);而且脑梗死在治疗和有效控制后D-D和 hs-CRP含量明显下降(P＜0.01).结论血中D-D和 hs-CRP与青年急性进展型脑梗死的发生、发展及预后有密切关系,可作为评估的指标之一,对于脑梗死的进展预测和干预处理有一定临床价值.
목적 탐토청년급성진전형뇌경사환자진전여치료전후혈중D-이취체(D-D)、고민 C-반응단백(hs-CRP)함량변화여뇌경사발전적관계.방법 선택급성뇌경사 A 조(미발생진전)30례、B조(발생진전)20례화정상대조조50례분별측정기hs-CRP、D-D진전급치료전후함량병가이분석.결과 청년급성진전형뇌경사조D-D화 hs-CRP함량명현고우대조조화비진전형뇌경사조(P＜0.01); D-D화 hs-CRP함량경통계학처리정정상관(r=0.64,P＜0.01);이차뇌경사재치료화유효공제후D-D화 hs-CRP함량명현하강(P＜0.01).결론 혈중D-D화 hs-CRP여청년급성진전형뇌경사적발생、발전급예후유밀절관계,가작위평고적지표지일,대우뇌경사적진전예측화간예처리유일정림상개치.
Objective To study the correlation between the levels of D-Dimer(D-D),high sensitive C-reactive protein(hs-CRP) in serum of the young patients with acute progressive cerebral infarction before and after the proceeding and treatment. Methods Levels of hs-CRP, D-D were detected respectively in serum of the 20 young patients with acute progressive cerebral infarction, the 30 young patients with acute non- progressive cerebral infarction and 50 healthy people sampled as control group and correlation were analysed before and after the proceeding and treatment. Results Compared with healthy person and young patients with non-progressive cerebral infarction, the levels of D-D and hs-CRP in serum of young patients with progressive cerebral infarction were significantly higher (P＜0.01). The level of D-D was positively correlated with that of hs-CRP,The levels of D-D and hs-CRP in serum of patients with cerebral infarction were significantly lower than before after having been treated and intervented effectively. Conclusions The levels of D-D,hs-CRP are closely related to the existence and development of the young patients with cerebral infarction. The levels of D-D and hs-CRP can be used as one of the assessment indexes of the young patient's conditions and is helpful for clinic forecast and intervention of acute progressive cerebral infarction.