CAJ | 학술논문

目的探讨波强(WI)技术评价原发性高血压患者血流动力学变化的临床应用价值.方法对36例原发性高血压患者和30名年龄匹配的健康成人的颈动脉进行超声扫查,应用WI软件获取WI曲线,测量收缩早期峰值(W1)、收缩晚期峰值(W2)、收缩中期负向区面积(NA)、心电图R波顶点至W1的时间间隔(R-1st)、W1至W2的时间间隔(1~(st)-2~(nd))及时间标化后的R-1_(HR)~(st)、1~(st)-2~(nd)HR等参数.结果 ①与正常对照组比较,原发性高血压组W1值升高,差异有统计学意义(P＜0.01),两组间W2值、NA值、R-1st、1~(st)-2~(nd)、R-1_(HR)~(st)、1~(st)-2(_(HR)~(nd))差异无统计学意义(P＞0.05).②W1值与脉压、收缩压呈显著正相关(r=0.66和r=0.55,P＜0.01),W2值与脉压、收缩压亦呈显著正相关(r=0.62和r=0.44,P＜0.01),W1值、W2值与年龄和DBP无相关性(P＞0.05).结论 WI技术提供的血流动力学参数为临床综合评价高血压患者的心脏、血管功能及其相互作用提供新方法.
목적 탐토파강(WI)기술평개원발성고혈압환자혈류동역학변화적림상응용개치.방법 대36례원발성고혈압환자화30명년령필배적건강성인적경동맥진행초성소사,응용WI연건획취WI곡선,측량수축조기봉치(W1)、수축만기봉치(W2)、수축중기부향구면적(NA)、심전도R파정점지W1적시간간격(R-1st)、W1지W2적시간간격(1~(st)-2~(nd))급시간표화후적R-1_(HR)~(st)、1~(st)-2~(nd)HR등삼수.결과 ①여정상대조조비교,원발성고혈압조W1치승고,차이유통계학의의(P＜0.01),량조간W2치、NA치、R-1st、1~(st)-2~(nd)、R-1_(HR)~(st)、1~(st)-2(_(HR)~(nd))차이무통계학의의(P＞0.05).②W1치여맥압、수축압정현저정상관(r=0.66화r=0.55,P＜0.01),W2치여맥압、수축압역정현저정상관(r=0.62화r=0.44,P＜0.01),W1치、W2치여년령화DBP무상관성(P＞0.05).결론 WI기술제공적혈류동역학삼수위림상종합평개고혈압환자적심장、혈관공능급기상호작용제공신방법.
Objective To observe hemodynamic changes in patients with primary hypertension with wave intensity (WI). Methods Carotid arteries of 36 patients with primary hypertension and 30 age-matched normal controls were examined with imaging technique of WI. The following parameters were measured: the first wave peak in early ejection (W1), the second wave peak in late ejection (W2), the negative area during the mid-ejection (NA), the interval between the R wave of the ECG and the first peak of W1 (R-1st), the interval between the first peak and the second peak (1~(st)-2~(nd)), the ratio of R-1st and a cardiac cycle time R-1_(HR)~(st)) and the ratio of 1~(st)-2~(nd) , as well as one cardiac cycle time (1~(st)-2(_(HR)~(nd)). Results ①W1 in primary hypertension group increased compared with those of normal controls (P＜0.01), while no significant difference of W2, NA, R-1st, 1~(st)-2~(nd), R-1_(HR)~(st), 1~(st)-2_(nd)~(HR) was detected (P＞0.05). ②Both W1 and W2 correlated positively with pulse pressure (PP) and systolic blood pressure (SBP) (r=0.66, 0.55, P＜0.01;r=0.62, 0.44, P＜0.01). W1, W2 and age, DBP were not related significantly (P＞0.05). Conclusion The hemodynamic parameters of WI technology provide a new way to evaluate the dynamics of the heart and vascular system and their interaction.