CAJ | 학술논문

目的了解2007年陕西省黄陵县克山病发病情况.方法将陕西省黄陵县克山病重病区店头镇3个村村民和腰坪乡中心小学学生作为监测对象进行心电图等检查,用以筛检克山病患者,并对全县已知潜在型克山病(简称潜克)和慢型克山病(简称慢克)患者进行X线胸片检查.荧光分光光度法检测病区患者、病区健康人群(内对照)、非病区健康人群(外对照)血硒及儿童发硒水平.结果店头镇和腰坪乡无急型、亚急型克山病发生,潜、慢克总检出率为3.92%(35/893),新发潜克1例,克山病患者心电图异常改变主要表现为ST-T改变.对全县潜、慢克患者83例进行X线胸片检查,心胸比例正常者27例,轻、中度增大者各20例.显著增大者16例.病区患者及内对照、外对照人群血清含硒量分别为(38.67±19.58)、(48.55±22.36)、(67.29±17.32)μg/L,组间比较差异有统计学意义(F=16.291,P<0.01);病区患者和内对照血硒明显低于外对照(P<0.01).病区患者血硒明显低于内对照(P<0.01).店头镇、腰坪乡中心小学儿童和非病区儿童发硒水平分别为(0.376±0.101)、(0.372±0.085)、(0.436±0.085)μg/L,组间比较差异有统计学意义(F=17.032,P<0.01);病区儿童发硒均明显低于非病区(P<0.01).结论 2007年陕西省黄陵县克山病检出率有所下降,而潜克仍有新发,可能与病区居民仍处于低硒状态有关.
목적 료해2007년합서성황릉현극산병발병정황.방법 장합서성황릉현극산병중병구점두진3개촌촌민화요평향중심소학학생작위감측대상진행심전도등검사,용이사검극산병환자,병대전현이지잠재형극산병(간칭잠극)화만형극산병(간칭만극)환자진행X선흉편검사.형광분광광도법검측병구환자、병구건강인군(내대조)、비병구건강인군(외대조)혈서급인동발서수평.결과 점두진화요평향무급형、아급형극산병발생,잠、만극총검출솔위3.92%(35/893),신발잠극1례,극산병환자심전도이상개변주요표현위ST-T개변.대전현잠、만극환자83례진행X선흉편검사,심흉비례정상자27례,경、중도증대자각20례.현저증대자16례.병구환자급내대조、외대조인군혈청함서량분별위(38.67±19.58)、(48.55±22.36)、(67.29±17.32)μg/L,조간비교차이유통계학의의(F=16.291,P<0.01);병구환자화내대조혈서명현저우외대조(P<0.01).병구환자혈서명현저우내대조(P<0.01).점두진、요평향중심소학인동화비병구인동발서수평분별위(0.376±0.101)、(0.372±0.085)、(0.436±0.085)μg/L,조간비교차이유통계학의의(F=17.032,P<0.01);병구인동발서균명현저우비병구(P<0.01).결론 2007년합서성황릉현극산병검출솔유소하강,이잠극잉유신발,가능여병구거민잉처우저서상태유관.
Objective To monitor the prevalence of Keshan disease in Huangling County, Shaanxi Previnee in 2007. Methods All local residents in surveinance area of Keshan disease in Diantou and Yaoping Township of Huangling County, were surveyed and given overall examinations by electrocardiography. The patients of latent and chronic Keshan disease were examined by X-ray. The selenium contents in blood and hair were monitored by fluorospectrophotometry in surveillance and non-surveillance areas. Results No new ease of acute or sub-acute patient was found. Latent and chronic patients detected accounted for 3.92% (35/893). Only 1 ease of new latent Keshan disease was newly found. Major feature of electrocardiographic abnormality was ST-T change. By X-ray, there were 27 eases with a normal heart, 20 eases with mild enlargement, 20 eases with medium enlargement, and 16 eases with marked enlargement. Serological selenium eoncentrations were (38.67±19.58), (48.55±22.36), (67.29±17.32)μg/L, respectively in patients, internal and external eontrols(F=16.291 ,P<0.01). Selenium contents of children's hair were (0.376±0.101), (0.372±0.085), (0.436±0.085)μg/L, respectively(F= 17.032, P<0.01). Conclusions Cases of diagnosed Keshan disease were decreased compared with the previous years. There were new eases of latent Keshan disease in Huangling County, Shaanxi Province.