CAJ | 학술논문

目的探讨生长抑素(奥曲肽)治疗甲状腺相关性眼病的疗效.方法将42例甲状腺相关性眼病(TAO)患者随机分为A、B二组,每组21例.A组眶内注射生长抑素(奥曲肽)100μg,;B组眶内注射地塞米松5mg.各组均每2周注射1次,连续注射6次.结果 (1)眼球突出度:A组治疗后3个月较治疗前明显减轻(P<0.05);B组治疗后3个月较治疗前无明显减轻(P＞0.05);(2)眼球运动障碍及复视例数:A组治疗后(23.8%)比治疗前(57.1%)明显减少(P<0.05);B组治疗后(33.3%)比治疗前(52.4%)无明显减少(P＞0.05).结论眶内注射生长抑素治疗甲状腺相关性眼病是有效和安全的.
목적 탐토생장억소(오곡태)치료갑상선상관성안병적료효.방법 장42례갑상선상관성안병(TAO)환자수궤분위A、B이조,매조21례.A조광내주사생장억소(오곡태)100μg,;B조광내주사지새미송5mg.각조균매2주주사1차,련속주사6차.결과 (1)안구돌출도:A조치료후3개월교치료전명현감경(P<0.05);B조치료후3개월교치료전무명현감경(P＞0.05);(2)안구운동장애급복시례수:A조치료후(23.8%)비치료전(57.1%)명현감소(P<0.05);B조치료후(33.3%)비치료전(52.4%)무명현감소(P＞0.05).결론 광내주사생장억소치료갑상선상관성안병시유효화안전적.
Objective To appraise the effect of intraorbital injection of Octreotide in patients with thyroid associated ophthalmopathy(TAO).Methods Forty-two cases of patients with TAO were randomly allocated into two groups:patients in group A was injected with 0.ling of Octreotide;patients in group B was injected with 5mg doxamethasone.Each group received the injection once every two weeks for six times.Results(1)The degree of exophthalmos in group A was significantly lower than that in group B at 3 months post-injection(P＜0.05);(2)The case of eyeball motion hinder and diplopia in group A was significantly less than that in group B at 3 months post-injection(P＜0.05).Conelusions Treatment for TAO with intraorbital injection of Octreotide is effective and safe.