CAJ | 학술논문

目的探讨老年患者对比剂肾病(CIN)的发生率与心脏-脚踝血管指数(CAVI)间的关系.方法对60岁及以上行经皮冠状动脉介入(PCI)的患者264例,进行CAVI测定,并分为CAVI≥9.0组(122例)及CAVI＜9.0组(142例),2组患者分别于术前和术后24,48 h行血清肌酐(SCr)及BUN测定及相应的生化检查,根据CockcroftGault公式计算出内生肌酐清除率(Ccr).对2组患者造影前后各项指标的变化及CIN的发生率进行比较.结果 2组患者使用对比剂24～48 h后SCr均有明显升高,Ccr明显降低,CAVI≥9.0组变化更明显,差异均有统计学意义(P＜0.05或P＜0.01),并且CIN的发生率高(6.56%比2.27%,P＜0.05).结论 CAVI增高与CIN的发生有一定的相关性,可作为介入术前评估CIN风险的一项指标.
목적 탐토노년환자대비제신병(CIN)적발생솔여심장-각과혈관지수(CAVI)간적관계.방법 대60세급이상행경피관상동맥개입(PCI)적환자264례,진행CAVI측정,병분위CAVI≥9.0조(122례)급CAVI＜9.0조(142례),2조환자분별우술전화술후24,48 h행혈청기항(SCr)급BUN측정급상응적생화검사,근거CockcroftGault공식계산출내생기항청제솔(Ccr).대2조환자조영전후각항지표적변화급CIN적발생솔진행비교.결과 2조환자사용대비제24～48 h후SCr균유명현승고,Ccr명현강저,CAVI≥9.0조변화경명현,차이균유통계학의의(P＜0.05혹P＜0.01),병차CIN적발생솔고(6.56%비2.27%,P＜0.05).결론 CAVI증고여CIN적발생유일정적상관성,가작위개입술전평고CIN풍험적일항지표.
Objective To investigate the relation between Cardio-ankle vascular index ( CAVI) and incidence of radiographic contrast nephropathy in senile patients after coronary angiography. Methods Two hundreds and sixty-four cases over 60 years were divided into two groups according to the value of CAVI. Serum creatinine and blood urea nitrogen and chemical inspection were measured before coronary angiography (CA) and on the 1st and 2nd days after CA. Results The value of serum creatinine and blood urea nitrogen 24 h and 48 h after CA in CAVI ≥9.0 group were increased (P<0.05) than those in CAVI <9.0 group. The occurrence of radiographic contrast nephropathy in CAVI ≥9.0 group was higher than that in CAVI <9.0 group. Conclusion CAVI is a risk factor of the incidence of radiographic contrast nephropathy in senile patients after CA.