中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2010年
1期
15-16,19
,共3页
卵巢癌%CD44v6%免疫组化
卵巢癌%CD44v6%免疫組化
란소암%CD44v6%면역조화
Ovarian cancer%CD44v6%Immunohistochemistry
目的 探讨CD44v6在卵巢癌中的表达情况及其与卵巢癌临床病理特征之间的关系,进一步阐明CD44v6在卵巢癌侵袭和转移过程中的作用.方法 通过免疫组化SP法检测在CD44v6正常卵巢组织、卵巢良性、交界性、恶性肿瘤组织中的表达.结果 CD44v6在卵巢癌中的表达与肿瘤的分化程度、肿瘤的临床分期及有无淋巴结转移有关,差异有统计学意义,而与上皮性肿瘤中的不同组织学类型无关.结论 CD44v6在正常卵巢组织中不表达,在卵巢上皮性癌中呈高表达,并与临床分期、分级、淋巴结转移有关,提示CD44v6的表达可能与卵巢上皮性癌的发生、发展有关.
目的 探討CD44v6在卵巢癌中的錶達情況及其與卵巢癌臨床病理特徵之間的關繫,進一步闡明CD44v6在卵巢癌侵襲和轉移過程中的作用.方法 通過免疫組化SP法檢測在CD44v6正常卵巢組織、卵巢良性、交界性、噁性腫瘤組織中的錶達.結果 CD44v6在卵巢癌中的錶達與腫瘤的分化程度、腫瘤的臨床分期及有無淋巴結轉移有關,差異有統計學意義,而與上皮性腫瘤中的不同組織學類型無關.結論 CD44v6在正常卵巢組織中不錶達,在卵巢上皮性癌中呈高錶達,併與臨床分期、分級、淋巴結轉移有關,提示CD44v6的錶達可能與卵巢上皮性癌的髮生、髮展有關.
목적 탐토CD44v6재란소암중적표체정황급기여란소암림상병리특정지간적관계,진일보천명CD44v6재란소암침습화전이과정중적작용.방법 통과면역조화SP법검측재CD44v6정상란소조직、란소량성、교계성、악성종류조직중적표체.결과 CD44v6재란소암중적표체여종류적분화정도、종류적림상분기급유무림파결전이유관,차이유통계학의의,이여상피성종류중적불동조직학류형무관.결론 CD44v6재정상란소조직중불표체,재란소상피성암중정고표체,병여림상분기、분급、림파결전이유관,제시CD44v6적표체가능여란소상피성암적발생、발전유관.
Objective To discuss the expressions of cell - surface adhesive molecules CD44v6 was investigated between the expressions and clinical patho - characteristic were also analyzed. To elucidate the effects of CD44v6 on invasion and metastasis of ovarian cancer, the correlation of CD44v6 was also analyzed. Methods The expression of CD44v6 in normal, benign, borderline and malignant cancer were detected by immunohistochemistry. Results There was significant difference between CD44v6 and degree of differentiation or clinical stage(P ＜ 0.05). Conclusions CD44v6 doesn't express in normal ovarian tissues, express highly in epithelial ovarian cancer and have relationship with clinical stage, clinical stage and lymph node metastasis. It suggests that the expressions of CD44v6 may have relationship with occurrence and development of epithelial ovarian cancer.
